Hey, you retarded, uneducated fuks. I just pulled up my copy of Harrison's Internal Medicine. Chapter 349.

Let's have a look, shall we?

Here are potential disorders of sexual development:
47,XXY (Klinefelter's syndrome and variants); 45,X (Turner's syndrome and variants); 45,X/46,XY mosaicism (mixed gonadal dysgenesis); 46,XX/46,XY (chimerism/mosaicism);

Of those with 46XY, there are the following conditions that can occur: disorders of gonadal (testes) development, disorders in androgen synthesis or action, other factors

-Testes development: Complete or partial gonadal dysgenesis (e.g., SRY, SOX9, SF1, WT1, DHH), Impaired fetal Leydig cell function (e.g., SF1/NR5A1, CXorf6/MAMLD1), Ovotesticular DSD, Testis regression
-Androgen synthesis:
I)Disorders of androgen biosynthesis, including LH receptor (LHCGR) mutations,Smith-Lemli-Opitz syndrome,Steroidogenic acute regulatory (STAR) protein,Cholesterol side-chain cleavage (CYP11A1),3beta-Hydroxysteroid dehydrogenase II (HSD3b2),17alpha-Hydroxylase/17,20-lyase (CYP17A1), P450 oxidoreductase (POR),17beta-Hydroxysteroid dehydrogenase III (HSD17b3) 5alpha-Reductase II (SRD5A2)
II)Disorders of androgen action, including Androgen Insensitivity syndrome, Drugs and environmental modulators
-Other factors:Syndromic associations of male genital development, Persistent müllerian duct syndrome,Vanishing testis syndrome,Isolated hypospadias, Congenital hypogonadotropic hypogonadism, Cryptorchidism,Environmental influences

Of those with 46XX, there are the following conditions that can occur: disorders of gonadal (ovary) development, androgen excess, other factors
-Ovary development: Gonadal dysgenesis, Ovotesticular DSD, Testicular DSD (e.g., SRY+, dup SOX9, RSPO1)
-Androgen excess:
I) Fetal: 3beta-Hydroxysteroid dehydrogenase II (HSD3b2?),21-Hydroxylase (CYP21A2?),P450 oxidoreductase (POR?)11beta-Hydroxylase (CYP11B1?),Glucocorticoid receptor mutations
II) Fetoplacental: Aromatase deficiency (CYP19),Oxidoreductase deficiency (POR)
III) Maternal: Maternal virilizing tumors (e.g., luteomas), Androgenic drugs
-Other: Syndromic associations (e.g., cloacal anomalies),Müllerian agenesis/hypoplasia (e.g., MRKH),Uterine abnormalities (e.g., MODY5),Vaginal atresia (e.g., McKusick-Kaufman),Labial adhesions

Now, these are all the ways PHYSIOLOGICALLY intersex and trans people can occur NATURALLY. This is not in the person's head. We can directly trace it back to a problem with a particular protein abnormality, chromo****l excess or deficiency, or exposure to environmental hormones or drugs while in the womb. None of this is "a mental disease" even though mental health complications will, understandably arise in people with these conditions.

You people are a bunch of heartless fuks with zero understanding of biology and medicine who are attempting to dictate that the universe is the way you want it to be because you are made uncomfortable by the idea that maybe your God fuked up. Sorry, to break it to you fuking hicks, but you can see very clearly that there is no perfect process in nature. Embryonic development can and does go wrong sometimes, and the few people who are born with conditions should not be treated like garbage for it.

With all due respect, which is absolutely none, go learn some things before you fuking talk.
And regarding the ? on the proteins, that is because while they know the deficiency or aberration, they cannot be entirely clear on the cause since those were abnormalities that tend to occur in the fetus.

There are people with mental illnesses who choose to become trans/intersex, but NONE of what I posted had anything to do with that. What I posted are ACTUAL, REAL physiological conditions that fuking happen to people. So, you can fuk off acting like it doesn't happen because it definitely does, *******s.

I actually had to waste a lot of my time copy pasting this from the fuking ebook, and I had to add all the alphas and betas in because it doesn't copy paste. Why did I do this? So that maybe one of u fuking idiots will change your mind or at least be inspired to read more about it. Maybe then you will understand and have a bit more understanding of trans ppl, biology, and life in general.

I am just explaining why trans ppl should not be attacked so much. I defend biology and get mocked and negged. You worship a man who can't multiply 17 x 6. This is the fuking world we live in. The fuking idiocracy is real. It's one thing when you disagree with me politically, and it's another thing when you ignore science. You should all be ashamed of yourselves. Fuking fist yourselves.

OPEN SOME FUKING BOOKS AND READ SOMETHING GOD DAMNIT.

keep your fetish to yourself

but i admire you for standing up for your trans boyfriend

Her makeup is on point tho.

Who know what else we call a mental disorder? Mental illness.

So read some books?

okay

so if it's 100% physical it would be easy to weed out who is lying who isn't and be able to do an objective test to see whether someone is trans right?

and after reading more what you posted has literally nothing to do with trans and even the trans community would tell you that you are retarded, syndromes that cause underdeveloped bodies have absolutely nothing to do with the trans movement you ignorant pretentious *******.

Surely this will change some minds.

WTF are u talking about? Tons of ppl who are trans have one of the aforementioned conditions.

And if u knew how to read (clearly you don't), you'd see that I never said it was 100% physical. I said that SOME cases of trans people have a physiological basis. Actually, if you checked carefully enough, wanting to cut ur fuking dick of clearly indicates there is something wrong with your brain, so there almost certainly is an actual physiological cause somewhere. The mental IS the physical. You think with your brain. So, even in the cases which aren't explained previously, it just means science hasn't caught up to the point yet where we can understand and classify human thought and what went wrong in the brain. Wanting to cut your dink off is maladaptive so there is clearly something fuked if an otherwise fertile and functional man wants to do this. Think about it, retards.

A large number of trans people have some type of aforementioned direct physiological issue -- especially the ones who undergo gender reassignment and hormone therapy.

I realize some of u *******s are triggered, but u need to understand there are ppl out there born with conditions they didn't choose.

should be easy to find a source then, or are you just talking out your ass and you happened to learn about some syndromes people are born with and trying to tack them to the trans movement to sound smart?

What percent of people born with these syndromes are trans? What percent of people that are trans don't have these syndromes? You are aware that these are easily testable and identifiable genetic mutations right?so with you're updated post you're someone that believes trans people that wish to go through with the full transition are wrong in the head? Strong fckin back pedal you *******, don't try and talk down on others then revert back to saying you agree that many have mental issues when someone calls you a retard.

I think the "attacks" you perceive is more towards the media focus on trans issues and less on adult trans people themselves. It will never not be weird, and most would rather not have it in their face as often as it has been, especially seeing as how the trans population is extremely small.

There is also very bad backlash against trans related things because kids are involved now. Most people are willing to tolerate just about anything an adult does that doesn't negatively impact others, but almost everyone feels some kinda way once you involve kids.

shove some of that copenhagen up your agnus boyo

you thinking about getting a vagina so you can lose your vcard brah?

bang all the dudes you want to brah

Dude, what happened? I feel like you're putting undue onus on yourself to fight a battle that doesn't need to be fought.

Did someone trigger you personally?

People are gonna post things here like "I like trans women" and other people are gonna write "I don't like trans women". If you like what you see, enjoy. If someone writes something you don't like, let it go.

Whatever is upsetting you, it's ok to be upset but the people here can't hurt you and nobody here is going to be swayed by anyone else here unless it's a car thread and someone says to buy a Subaru instead of a Toyota.

So what you're saying is...it's a mental illness?

he banged a tranny and this is his cope thread

I think he's saying he wants to bang trannies.

It's more of a cry for help than anything.

Best cliffs I've seen in a long time.

I'm not backpeddling anything. I said exactly what I said. You invented a position I didn't take, and now I don't even know what you are attempting to argue. I never said ALL trans people have a physiological basis directly, as known. (I do however, condtend that they do all have a physiological basis at some point, as I explained earlier. We just don't know exactly how the brain works. As I said, mental activities are physical in nature and have to do with the functioning of the brain.) Regarding the exact percentage of people who are trans that have DSD, I don't know, but I know it is high. Supposedly gender dysphoria occurs in 1/30,000 male births and 1/100,000 female births. Meanwhile, one in 1,666 births are not XX or XY. And one 1/130,000 births has partial androgen insensitivity syndrome.

http://www.isna.org/faq/frequencythis is just intersex/DSD. This would imply that a significant portion of people who everyone calls "trannies" (people with some sort of gender reassignment surgery/hormones) are also intersex. It is difficult to find the exact statistics, but what I showed you can be used to estimate the number.

I just love how mad everyone gets over it. Also, I feel people are misinformed about it. It's fun to piss everyone off and also be right about things.

trannies go home!

OFC I do not deny the links. I even said most people who suffer from DSD inevitably develop some mental illness due to their condition as well. The two go hand in hand.

But even those who do not have a known underlying physiological condition causing this (we only know the gonadal stuff really well), there could be other physiological stuff going on the brain that we do not understand. In fact, there certainly is. Any claim about "mental illness" IS inevitably fundamentally physiological in nature. That is something a lot of people don't understand. They write off mental illness as if it isn't a real physiological thing. Newsflash guys, you think with your brains. It means there is an abnormality in the way your brain functions.

Sometimes, we like to argue it was stimuli, but you have to realize stimuli elicit actual physiological changes in brain function. Exposure to those stimuli can actually fuk your brain up PHYSICALLY. This is the entire basis of medical treatment of depression, for example.

Calling us all hicks will surely work you ****ing bigot.


So not only are you one gigantic racist, you are also a bigot now. Gjdm.

Lets make things clear for people.

The mental illness is called gender dysphoria. The current available medical TREATMENTS for gender dysphoria are: hormonal treatments or physical treatments such as sex changes. Transgender and transexual humans are the end result of the current medical treatment, NOT the end result of their mental illness.

It is litteraly a large scale experiment to determine if either of these treatments for gender dysphoria actually work. It probably is not the proper medical treatment since a huge number of people that had a sex change are suicidal or commit suicide. Physicians are now slowly moving against that treatment for gender dysphoria.

He's just mad no one cares about his posts in R/P.