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ยป EPA in fish/flax oil may be anti cancer (2018 study)
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post 1632022773 02-21-2021, 11:49 PM
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EPA in fish/flax oil may be anti cancer (2018 study)

Eicosapentaenoic acid (EPA) is required for biological processes, but humans are unable to synthesize them and must be obtained from dietary sources. EPA has been used as an antitumor agent but the molecular mechanisms for the regulation of tumor microenvironment immunity by EPA are still unknown. The results demonstrated that EPA can activate host antitumor immunity by inhibiting tumor IDO expression. Therefore, our finding suggests that EPA can be enormous potential for cancer immunotherapy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158658/

Looks like EPA is important to the body. Time to give fish and flaxseed pills a 2nd chance
post 1632022863 02-21-2021, 11:51 PM
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Also can increase estrogen with flax but yeah it is extremely healthy in right consumption.
Eating "clean" doesn't mean eating "healthy"

Eating "healthy" doesn't mean=muscle mass-Olympia2018


Yeah Baby! Yeah!!!-800 pound deadlift

At weddings all the old ppl say "you're next". At funeral's I tell them "you're next"

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post 1632031463 02-22-2021, 05:16 AM
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Originally Posted By Olympia2018
Also can increase estrogen with flax but yeah it is extremely healthy in right consumption.
Interesting, do you have a link? I did a quick search and found that DHA degrades the estrogen receptor alpha, and promotes the formation of DHA/EPA from ALA:
https://link.springer.com/article/10...745-007-3117-6
https://www.sciencedirect.com/scienc...55286309000527

This study says "N-3 PUFA treatment blunts the activation of EGFR, Erk1/2, AKT signaling by E2 stimulation" which indicates that EPA/DHA blocks some of the harmful effects of estrogen
https://sci-hub.st/10.1371/journal.pone.0052838

That EGF-receptor + ERK1/2 is also the same pathway that DHT creates strength from (aka mapk pathway). The ERK pathway allows cells to overcome stress/oxidation and other hazards to continue survival. Good sometimes for building muscles, but bad for health/cancer/lifespan. DHT and the ERK/mapk pathway are not surprisingly implicated in cancer

ERK/MAPK pathway implicated in 1/3rd of all cancershttps://pubmed.ncbi.nlm.nih.gov/22569528/
post 1632033163 02-22-2021, 06:12 AM
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Was just reading about high dose fish oil to mitigate almost all damage from concussions.

High quality fish oil ftw

https://www.prweb.com/releases/concu...web4500964.htm
post 1632033563 02-22-2021, 06:23 AM
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What about cod liver oil? I take it every day
post 1632037953 02-22-2021, 07:47 AM
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Originally Posted By Evlve
Was just reading about high dose fish oil to mitigate almost all damage from concussions.

High quality fish oil ftw

https://www.prweb.com/releases/concu...web4500964.htm
15g of fish oil will add up $ quickly. Flaxseed has ALA which about 5% is converted to EPA and 0.5% to DHA. I wonder if some vitamin or supplement would increase that. Flaxseed oil is quite a bit cheaper and very easy to get 15g a day.
Originally Posted By Lord_Lemon
What about cod liver oil? I take it every day
Looks like it has a decent amount of EPA/DHA, about 200mg per 1g, but look out for too much vitamin A, cod liver has a lot of that.
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