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Into- Mountaineering, running & Djent/Progressive music.
Anti- Lack of accountability. Censorship, fat acceptance, & current wave feminism. That's why I left the UK.
PRs: Highest mt. - 2962m (Zugspitze), Longest day hike - 70km.

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*Look at reflection in car window and flex every time crew*
*Use half the roll to wipe after a poo crew*
*Fart in the gym and blame rotten smell on faulty ventilation crew*
*Fart at home and blame it on the dog crew*
*Watch neutron-star density poop mock me as water flushes around it and it stays put crew*
*Drive 2 minutes in the summer and back of shirt gets completely wet crew*
*Coffee black as midnight on a moonless night crew*
*Fat shame my cat on a daily basis crew*

Gender Identity: Miscer pronouns: ****/****g‏‏‎ot

Traitors gonna trait

Currently playing: Dynasty Warriors 8: Xtreme Legends

*Look at reflection in car window and flex every time crew*
*Use half the roll to wipe after a poo crew*
*Fart in the gym and blame rotten smell on faulty ventilation crew*
*Fart at home and blame it on the dog crew*
*Watch neutron-star density poop mock me as water flushes around it and it stays put crew*
*Drive 2 minutes in the summer and back of shirt gets completely wet crew*
*Coffee black as midnight on a moonless night crew*
*Fat shame my cat on a daily basis crew*

A million miles away - I don't.. feel.... anything.
http://www.youtube.com/watch?v=PXGZu4yxjW0

Gender Identity: Miscer pronouns: ****/****g‏‏‎ot

Traitors gonna trait

Currently playing: Dynasty Warriors 8: Xtreme Legends

No man has the right to be an amateur in the matter of physical training. It is a shame for a man to grow old without seeing the beauty and strength of which his body is capable.

-Socrates

All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.

- Arthur Schopenhauer

Originally Posted By TappingTheZen⏩

For me, i have no opinion about when or if we'll see more major sides - i don't know, and there's no data on the long term effects and that's exactly the problem. I'm well educated, and i don't think it's unreasonable to opt out of a vaccine that i don't really need, when the long term effects are completely unknown, even though it may end up being fine.

The way you're approaching this is backwards in my opinion - you seem to imply that unless there's proof it isn't safe, we shouldn't have skepticism... whereas i think the sensible approach, and usual approach is to prove something IS safe long term before giving it to human populations. This is the entire purpose in the clinical trial system, and why many drugs take so long to be approved.

Why would i want to use the most poorly tested vaccine in history (in temporal terms, at least), that doesn't even finish stage 3 clinical trials until 2025? I would consider it in 2025 if the clinical trial data looks good, but again i reserve the right to reject it if i wish - it's not really anybody's right to tell me what i put in my body.

I think it's great we have the option of a vaccine for those who fall into a very vulnerable category or simply those who want it, but it should remain just that - an option, especially given the low mortality of covid.

What worries me more than the vaccine is the coercion, nobodies life should be made near impossible to live unless they take a vaccine that doesn't even finish its stage 3 clinical trials for years. I believe in freedom and liberty, and what i'm seeing from many governments, but especially the US right now is honestly horrifying to me.

Also, this view doesn't make me an 'anti-vaxxer', it makes me 'anti-guinea-pig'

So much this. And I think it muddies the issue, perhaps intentionally.It is possible to supportpeoplebeing allowed to be vaccinated by choiceand even to believe thatbeing vaccinated is the right choice for some peopleAND to also believe thatvaccine passports and mandates are totalitarian and at least bordering on immoral.

Originally Posted By seanb1979⏩

Biggest issue for me is it does not stop transmission and delta runs right through it. Other variants could be the same - there were 17 last I checked. Could be a lot more that just haven't been isolated.

Right. And Geer's assertion that widespread vaccination during an active pandemic would increase the number of variants thus increasing the odds of a more severe/novel mutation seems to be occuring.

There are a few different known avenues of escape from antibodies:



What happens if we get a 'bingo" with a more severe variant that hits all 4 escape routes?

According to Muller's ratchet, we should expect the ordinary process of evolutionary mutation to also lead to the virus tripping over itself. As random mutations that do not immediately harm the ability of a virus to survive pile up, the probability that further mutation results in an organism that can no longer survive piles up. This further puts weakening evolutionary pressure on a highly virulent asexual organism. This tendency works to our advantage---so long as we don't screw it up.

Sadly, either those running the mass vaccination program don't get it, or they just don't care to be honest about it.

It seems more likely that the sudden emergence of this "variant factory" story is a coordinated response to warnings about leaky vaccines put forth by vaccine expert Geert Vander Bossche, echoed in basic principle by evolutionary biologists Bret Weinstein and Heather Heying, along with evidence of dwindling vaccine efficacy. More importantly, it makes no sense. In order to understand why it makes no sense, consider the following contrasting scenarios:

1. In an unvaccinated population, mutations occur at random producing a wide genetic spread with very few progeny resulting in long lasting lineages (Muller's ratchet), with a selection pressure that favors those variants that can (a) win the competition of replication among its cousins within a host, and (b) not kill the host so that it can thrive in new hosts.

2.In a highly vaccinated population, mutations occur at random, but the genetic spread among versions of the virus is narrowed to those that can evade immunity, which has now been made more uniform among the vaccinated population. This further encourages such lineages even when they would not have won out within individual hosts in competition among its cousins. Such evasion increases chances of reinfection.

To be clear: every host is an evolutionary factory for viruses.What should concern us is the nature of streamlining of the process. A picture (even when it represents an oversimplification) is worth a thousand mutations. Variants that can escape immunity are shown in green. The others fail to pass through the sieve that represents the totality of a host's immune system.

On the emergence of the variants:

- TheAlpha variant emergedin the UK in October, which waswhen Oxford-AstraZeneca was holding vaccine trials there.

- TheBeta variant emergedin South Africa, and was first detected in December, 2020,at the tail end of trial periods for both Oxford-AstraZeneca and Pfizer vaccines. This variant carries three mutations in the spike protein.

- The Gamma variant was first detected in Japan, but soon after in Brazil, making the origin a little harder to determine.But since Japan has had far lower viral spread than Brazil,it makes the most sense that Brazil was the source. Both Oxford-AstraZeneca and Pfizer trialed their vaccines in Brazil.

- TheDelta variant was first detected in Indiain October, 2020.India hosted numerous vaccine trials including one for Oxford-AstraZeneca and one for Covishield.

It is noteworthy that variants of interest did not emerge during the early stages of the pandemic, despite mass spread of SARS-CoV-2 around the globe.That's a pretty huge sample size of unvaccinated people. But those that have emerged did so in geographies where vaccine trials were held---that is several variants from a far smaller genetic pool.

More here Part 1 and 2:

https://roundingtheearth.substack.co...n-and-immunity

https://roundingtheearth.substack.co...d-immunity-3ca

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"It was always the women, and above all the young ones, who were the most bigoted adherents of the party, the swallowers of slogans, the amateur spies and nosers-out of unorthodoxy." - George Orwell, 1984

LTC is the only heterosexual way.

Don’t have to wait, negative side effects are pretty immediate

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Lifted for 30 years

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"The flowers bloom, then wither... The stars shine and one day become extinct. This earth, the sun, the galaxies and even the big universe, someday will be destroyed. Compared with that, the human life is only a blink, just a little time. In that short time - people are born, laugh, cry, fight, are injured, feel joy, sadness, hate someone, love someone. All in just a moment. And then, are embraced by the eternal sleep called death."