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My Total & Free Test [pic] (am I fukked?) (doing SARM cycle rn)
07-31-2024, 07:29 PM
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#31
- LargePeter
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Originally Posted By WiseOldApe⏩
Given your post history, I'd like to thank ChatGPT for your response to my post.What do you mean the name doesn't mean anything? In the scientific community, the naming nomenclature means everything. It's a noun, adjective, and verb.
The Androgen Receptor (AR) is activated by a ligand. A ligand is a chemical structure that attaches to the receptor on the outside of the cell, causes a conformational change to the protein, and then sends a signal into the cell through a variety of means. In the case of an AR, once activated on the outside, the inside detaches, becomes what is known as a 'transcription factor' and moves into the nuclear to promote gene expression/regulation.
Whether an AR is activated by testosterone, ostarine, or magic, it will do the same thing once in the cell - a SERM may not technically be a steroid in chemical structure, but it will affect the body the same way.
I have not even looked into it, but because I have a STEM degree, I would assume that portion of the androgen receptors on which the ligand (such as a SERM or Test) binds will vary from cell type to cell type and even location - both in structure, and in amount.
The idea is for the SERM to target muscle cells and bone-cells (osteoblasts), but not prostate cells or hair follicles, for example.
Based on most (almost all) reports from bodybuilders, SERMS are not effective at purely building muscle whilst not affecting overall testosterone production.
The Androgen Receptor (AR) is activated by a ligand. A ligand is a chemical structure that attaches to the receptor on the outside of the cell, causes a conformational change to the protein, and then sends a signal into the cell through a variety of means. In the case of an AR, once activated on the outside, the inside detaches, becomes what is known as a 'transcription factor' and moves into the nuclear to promote gene expression/regulation.
Whether an AR is activated by testosterone, ostarine, or magic, it will do the same thing once in the cell - a SERM may not technically be a steroid in chemical structure, but it will affect the body the same way.
I have not even looked into it, but because I have a STEM degree, I would assume that portion of the androgen receptors on which the ligand (such as a SERM or Test) binds will vary from cell type to cell type and even location - both in structure, and in amount.
The idea is for the SERM to target muscle cells and bone-cells (osteoblasts), but not prostate cells or hair follicles, for example.
Based on most (almost all) reports from bodybuilders, SERMS are not effective at purely building muscle whilst not affecting overall testosterone production.
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07-31-2024, 07:30 PM
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#32
- LargePeter
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Originally Posted By OGfrom06⏩
Total Test: 189 ng/dL -LOWLocation: Kuntstralia
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07-31-2024, 07:40 PM
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#33
- WiseOldApe
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Originally Posted By LargePeter⏩
I have a degree in science. I am familiar with cellular biology, biochemistry, and molecular biology. Hence why I can educate you on these matters.Given your post history, I'd like to thank ChatGPT for your response to my post.
The only reason i am posting about this, is because the topic was brought up and I like to educate people on why taking experimental chemicals isn't always the best idea - and neither is it a good idea to take 'approved' compounds like ostarine, thinking they are side-effect free.
Based on anecdote, taking a cycle including tren and deca is more harmful than just test or anavar, but they still shut you down.
Also I accidentally wrote SERM in place of the intended term, SARM. Please take this into consideration if you're going to utilise that information.
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07-31-2024, 08:26 PM
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#34
- LargePeter
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Originally Posted By WiseOldApe⏩
lmaoI have a degree in science. I am familiar with cellular biology, biochemistry, and molecular biology. Hence why I can educate you on these matters.
The only reason i am posting about this, is because the topic was brought up and I like to educate people on why taking experimental chemicals isn't always the best idea - and neither is it to take 'approved' compounds like ostarine.
The only reason i am posting about this, is because the topic was brought up and I like to educate people on why taking experimental chemicals isn't always the best idea - and neither is it to take 'approved' compounds like ostarine.
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07-31-2024, 08:37 PM
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#35
- WiseOldApe
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Originally Posted By LargePeter⏩
Feel free to PM me if you ever need tutoring on anything related to the biological sciences. I know how intimidating it can be at first. You open up a research paper, don't understand the first word and then spend 30 minutes figuring out what it means in that particular context, since to understand one concept, there's prerequisite concept, term, or idea that needs mastering. I'm happy to explain it like you're 5.lmao
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07-31-2024, 10:25 PM
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#36
- LargePeter
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Originally Posted By WiseOldApe⏩
I'm quite fine thank youFeel free to PM me if you ever need tutoring on anything related to the biological sciences. I know how intimidating it can be at first. You open up a research paper, don't understand the first word and then spend 30 minutes figuring out what it means in that particular context, since to understand one concept, there's prerequisite concept, term, or idea that needs mastering. I'm happy to explain it like you're 5.

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07-31-2024, 10:35 PM
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#37
- WiseOldApe
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Originally Posted By LargePeter⏩
sureI'm quite fine thank you

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