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» What is so scary about getting Covid?
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post 1610773911 07-16-2020, 11:36 AM
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Originally Posted By stfudonny
the two people i know personally who got it (one lady in her 70s) had very mild symptoms soooo its like every other viral infection. some people get really sick, some people dont.
which is why there is a need to take the virus serious. There are too many unknowns. Some strains have the ability to kill 35 year olds, and others strains can be fought back by the immune system of 90 year old.
post 1610773961 07-16-2020, 11:36 AM
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Originally Posted By dabbmw2002
Pretty obvious, right?
Seems that way to me.

I believe that everyone should take precautions that they personally want and not have it dictated out to the masses.

If you’re concerned about the virus. Stay home.
If you think a mask helps protect you. Wear a mask.
If you think you could pass the virus to your grandparents. Don’t visit them.

I think that’s a completely reasonable course for an individual to take.

*Rant*
I hate the phrase, “we’re all in this together”. No, we’re not. I don’t want to join you in your ‘corona’ culture. I just want to be left alone and not be compelled to join your group so you can then say “we’re all in this together.”

But it seems like Karen’s, and others want to force others to be in their group and will try and take any means possible to make it happen.

(Of course, I’m using “you” in the general sense.)
/Rant*
post 1610774181 07-16-2020, 11:40 AM
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Originally Posted By Maestro
the "common cold" doesn't bind to ACE receptors disrupting blood pressure, cause pulmonary fibrosis permanently scarring your lungs or inhibit proper utilization of oxygen requiring a ventilator.
COVID-19 is a coronavirus, which is one of the three types of viruses that cause the common cold. Where do other coronaviruses bind to?

Let’s press it further. Can you concretely prove that it is the act of binding to a cells ACE receptor that is empirically causing those other symptoms that you wrote. I look forward to you explaining the biochemical process that causes that.
post 1610774791 07-16-2020, 11:45 AM
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Originally Posted By tank2003
wait...wut? so because someone you know got mild symptoms that means its just likeevery other infection? Tell that to the 140k people who died from it. (but i think those numbers reflect the death of every person who died with covid, not died BECAUSE of covid).Every other infectiontends to usually result in deaths because of complications like pneumonia and septicemia. COVID kills people BECAUSE its COVID. .
but thats the thing, viruses disrupt normal metabolic processes in the body, a person may die of a heart attack but if it was brought on by C19 and if they would otherwise be alive if not for C19 then the cause of death is from C19 pre-existing conditions be damned.
post 1610774951 07-16-2020, 11:49 AM
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Originally Posted By drFEEL
the tv says its scary so it must be scary
Can you show me the research you've studied that has lead you to believe that it isn't a big deal?
post 1610775521 07-16-2020, 11:55 AM
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Originally Posted By Maestro
Can you show me the research you've studied that has lead you to believe that it isn't a big deal?
Maybe that we're 6 months into this and still waiting to see deaths on biblical proportions as predicted? It was all bullchit at the start of the year and it still is. And f off with your lung damage and blood clotting lol, they tried their best to get that to catch on.
post 1610775601 07-16-2020, 11:56 AM
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Originally Posted By Maestro
which is why there is a need to take the virus serious. There are too many unknowns. Some strains have the ability to kill 35 year olds, and others strains can be fought back by the immune system of 90 year old.
Sorta like every other cold/flu virus ever?

You have done a magnificent job of scaring yourself into a tizzy.
post 1610775781 07-16-2020, 11:58 AM
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Originally Posted By epidox01
Good luck with your permanent lung damage goals of 2020.

And also, COVID-19 infection does not create lasting antibodies. Studies after studies show that people lose antibodies after 3+ months, in which case you get get infected again.

Also, studies find there are increased risks of blood clots, brain aneurysms, strokes, etc, etc.

No thx jeff
o rly, people have been reinfected have they?
post 1610777271 07-16-2020, 12:14 PM
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Originally Posted By saltypits
Sorta like every other cold/flu virus ever?

You have done a magnificent job of scaring yourself into a tizzy.
LOLz
6'2" @ 247lbs
post 1610777871 07-16-2020, 12:20 PM
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Had night sweats for a few days and that’s it. Of course a lot of people react badly to it. More than 90% of people in this country don’t give a crap about their health. Inactive, eat garbage all day, and don’t even get any damn sunlight. Almost everybody I’ve heard considered “healthy” that still reacted badly to the virus was not living a healthy lifestyle whatsoever.

Edit: I’m an RN. I’ve literally had multiple 90+ yr old patients get it and recover with almost no symptoms. They were only under my care for formalities/policy
post 1610778991 07-16-2020, 12:31 PM
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Originally Posted By MuscleXtreme
COVID-19 is a coronavirus, which is one of the three types of viruses that cause the common cold. Where do other coronaviruses bind to?

Let’s press it further. Can you concretely prove that it is the act of binding to a cells ACE receptor that is empirically causing those other symptoms that you wrote. I look forward to you explaining the biochemical process that causes that.
sure thing. I know you're being facetious, but I loved learning about this stuff when I was in school.. I've got my Bachelors in Biochemistry and minored in Microbiology.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188049/
The Abstract of a Peer reviewed article is the overview of the entire article. You can read the entire paper if you want for a more detailed analysis, but you can get the jest of their findings through the Abstract alone.


I know this is jargon heavy and there's an assumption of phyiological knowledge on the part of the reader, so i'll re-write the important bits in laymans terms;

ACE stands for Angiotensin Converting Enzyme

Angio=artery or vein
tension=constrict

the enzymes (special proteins that speed up chemical reaction in the body) that bind to ACE regulate the relaxation or constriction of veins and arteries regulating blood pressure.

a chain of proteins is called a polypeptide. There is a polypeptide backbone (like a spine) and the "ribs" attached to the spine are various chains of amino acids that branch off of it (the 20 essential amino acids to be exact glutamine proline valine tryptophan etc etc). The correct sequence of amino acids determines how a molecule, an enzyme (or in this case a virus) binds to a receptor. A strong binding affinity (not wanting to let go of the receptor site) is bad because it will not release, keeping at artery or vein in a permanent "ON" or "OFF" state, in other words, permanently relaxed veins or permanently constricted veins leading to prolonged decrease or increased in blood pressure (its the same reason why carbon monoxide poisoning is bad because it binds too strongly to erythrocytes (red blood cells) so they cannot release the oxygen they received).

ANYWAY, disrupted ACE receptors from Covid 19 cause a lowered ejection fraction due to low blood pressure. The Ejection Fraction is amount of blood that leaves the heart with each contraction. A low ejection fraction can lead to heart failure and a high ejection fraction leads to a heart attack.

The article goes on and on regarding other disease states, but I would be here forever and I have to get ready for work, lol.
post 1610780431 07-16-2020, 12:50 PM
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Originally Posted By BMXcaprisun
Edit: I’m an RN. I’ve literally had multiple 90+ yr old patients get it and recover with almost no symptoms. They were only under my care for formalities/policy
I guess anecdotes shape our opinions even at a subconscious level. I happen to be more weary of the virus because when I was working in a trauma ER we lost a 17 year old and a 28 year old and had a 12 year old survive, but with fibrosis of the left lung.

Maybe if I was in the presence of 90 year olds beating the virus like you I wouldn't be so concerned.

It is what it is.
post 1610785531 07-16-2020, 01:51 PM
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Originally Posted By Maestro
I guess anecdotes shape our opinions even at a subconscious level. I happen to be more weary of the virus because when I was working in a trauma ER we lost a 17 year old and a 28 year old and had a 12 year old survive, but with fibrosis of the left lung.

Maybe if I was in the presence of 90 year olds beating the virus like you I wouldn't be so concerned.

It is what it is.
Damn. Yeah you’re right, anecdotes do shape our opinions and to be honest I’m not mad about it. I’ve come to be extremely distrustful of anything I don’t see with my own eyes. We’ve seen recently how even in the best of medical journals there were bunk studies to push an agenda. Nothing is honest anymore.
post 1610797091 07-16-2020, 03:51 PM
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Originally Posted By Maestro
sure thing. I know you're being facetious, but I loved learning about this stuff when I was in school.. I've got my Bachelors in Biochemistry and minored in Microbiology.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188049/
The Abstract of a Peer reviewed article is the overview of the entire article. You can read the entire paper if you want for a more detailed analysis, but you can get the jest of their findings through the Abstract alone.


I know this is jargon heavy and there's an assumption of phyiological knowledge on the part of the reader, so i'll re-write the important bits in laymans terms;

ACE stands for Angiotensin Converting Enzyme

Angio=artery or vein
tension=constrict

the enzymes (special proteins that speed up chemical reaction in the body) that bind to ACE regulate the relaxation or constriction of veins and arteries regulating blood pressure.

a chain of proteins is called a polypeptide. There is a polypeptide backbone (like a spine) and the "ribs" attached to the spine are various chains of amino acids that branch off of it (the 20 essential amino acids to be exact glutamine proline valine tryptophan etc etc). The correct sequence of amino acids determines how a molecule, an enzyme (or in this case a virus) binds to a receptor. A strong binding affinity (not wanting to let go of the receptor site) is bad because it will not release, keeping at artery or vein in a permanent "ON" or "OFF" state, in other words, permanently relaxed veins or permanently constricted veins leading to prolonged decrease or increased in blood pressure (its the same reason why carbon monoxide poisoning is bad because it binds too strongly to erythrocytes (red blood cells) so they cannot release the oxygen they received).

ANYWAY, disrupted ACE receptors from Covid 19 cause a lowered ejection fraction due to low blood pressure. The Ejection Fraction is amount of blood that leaves the heart with each contraction. A low ejection fraction can lead to heart failure and a high ejection fraction leads to a heart attack.

The article goes on and on regarding other disease states, but I would be here forever and I have to get ready for work, lol.
Appreciate it. I’ve taken a biochemistry as a course - don’t have a bachelors in it though.

This is more convincing to me more than anything because there is actual science behind it, and I can tell from your knowledge and what I know that you’re not bull****ting.

Edit: Got through a big chunk of the article and the people it seems that people who already had some type of impairment in their ACE2 receptors were the ones that eventually died. Those were people with pre-existing heart conditions, diabetes.
, and reduced myocardial ACE2 expression.46 These patients also had a much more aggressive illness associated with earlier mortality. Additionally, bilateral pleural effusions were frequently observed during autopsy of SARS-CoV patients, further supporting the evidence of cardiac involvement. Individuals with preexisting diabetes mellitus, hypertension, and lung disease are at particular risk of COVID-19 infection37,47 and this is likely due to dysregulated RAS that occurs in these conditions.4,48
So what this sounds like to me, is if you have an illness that already impaired your ACE2 receptors, you could be screwed. Otherwise, if a normal person contracts Covid, the impairment could be the same as when caffeine temporarily binds with adenosine receptors, where a short term effect is felt, but if it were to occur for prolonged periods of time, mania could occur.
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