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03-05-2024, 05:03 PM
#781
Originally Posted By J.L.C.⏩
Never producing breast milk, the loss of the ability to have children, altering their voices, just to name a few..posted a great video of Chloe Cole discussing all the negative side effects she suffered…cause ya know, test effects women & children differently than fully developed men..
I dunno
The literature suggests very similar risk profiles for GAHT and HRT.
The literature suggests very similar risk profiles for GAHT and HRT.
Crazy you don’t address the negative aspects though..any reason for that?
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03-05-2024, 05:05 PM
#782
Originally Posted By Paul Kreul⏩
Still not sure why you keep trying to make it about children.
Never producing breast milk, the loss of the ability to have children, altering their voices, just to name a few..posted a great video of Chloe Cole discussing all the negative side effects she suffered…cause ya know, test effects women & children differently than fully developed men..
Crazy you don’t address the negative aspects though..any reason for that?
Crazy you don’t address the negative aspects though..any reason for that?
Also, I specifically mentioned risk profiles.
03-05-2024, 05:07 PM
#783
Originally Posted By J.L.C.⏩
Because test is being given to children
Still not sure why you keep trying to make it about children
https://www.pbs.org/wgbh/frontline/a...0bone%20growth .
But it’s dangerous for women nonetheless
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03-05-2024, 05:15 PM
#784
Originally Posted By J.L.C.⏩
So what age is acceptable?
Where do you get that idea?
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03-05-2024, 05:16 PM
#785
Originally Posted By Paul Kreul⏩
He doesn't know this???
No.. because test effects women & children differently especially at levels used for fully developed males lol
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03-05-2024, 05:20 PM
#786
Originally Posted By Dave22reborn⏩
He doesn't know this???
Oh he knows, he just feels
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
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03-05-2024, 05:21 PM
#787
Originally Posted By Paul Kreul⏩
Like so many libs, he can't go beyond first order thinking.
Oh he knows, he just feels
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
03-05-2024, 05:30 PM
#788
Originally Posted By Polaris⏩
B..b..BUT the benefits..
Like so many libs, he can't go beyond first order thinking.
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03-05-2024, 05:38 PM
#789
Originally Posted By Paul Kreul⏩
Oh he knows, he just feels
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
Lookin' pretty similar
03-05-2024, 05:44 PM
#790
Originally Posted By Paul Kreul⏩
He knows, but he just wants to troll. That’s why he says retarded things like “ The recommended serum levels of estradiol and testosterone are the same for those prescribed hormones for gender dysphoria as for those who are prescribed hormones for HRT.”
Oh he knows, he just feels
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
Benefit>dangers
Sucks cause when those FTM start taking test that an adult male would take & they lose all their hair they already are knocked down to a 4/10 by MISC standards.
It’s over before they even started
If a 40 year old female actually gets a competent provider who will give them care and oversee hormone therapy that involves testosterone, the dosage will be tiny and monitored closely for adverse effects. If a 20 year old female goes to her doctor and gets testosterone to “affirm her gender as male” she gets enough testosterone to start growing facial hair and all kinds of other sh!t, those two scenario aren’t even in the same ballpark with regard to what levels the doctors are “recommending” and the risk profile certainly isn’t the same either.
But again, he knows this and just wants to be obtuse.
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03-05-2024, 05:57 PM
#791
Combined Estrogen and Testosterone Use and Risk of Breast Cancer in Postmenopausal Women
Among women with a natural menopause, the risk of breast cancer was nearly 2.5-fold greater among current users of estrogen plus testosterone therapies (multivariate relative risk, 2.48; 95% confidence interval, 1.53-4.04) than among never users of PMHs
Consistent with the elevation in risk with increasing endogenous testosterone level, women using E&T therapies have a significantly increased risk of invasive breast cancer. These results are also consistent with studies showing that E&P therapies with synthetic testosterone-derived progestogens are associated with a greater risk of breast cancer compared with those with micronized progesterone.45 These results are especially important given the already apparent increase in trends and the expectation that more formulations containing testosterone will become specifically approved for and marketed to women.
https://jamanetwork.com/journals/jam...article/410682
High testosterone in women ups risk for cancer, diabetes, and metabolic disease
They revealed that women with genetically higher testosterone levels have a heightened risk of developing type 2 diabetes by 37 percent. On the other hand, men had a reduction of type 2 diabetes risk by 14 percent if they had higher testosterone levels.
The women also had a 51-percent increased risk of polycystic ovary syndrome (PCOS). PCOS was previously thought to have caused high testosterone levels.
Further, findings of the study unveiled that higher testosterone levels in women had been tied to a higher risk of developing cancer, including endometrial and breast cancer. In men, high levels of the hormone are linked to higher prostate cancer risk. The team concluded that there is a genetic component to testosterone levels in both sexes, but the effects were very different between men and women.
Using human genetics to understand the disease impacts of testosterone in men and women
https://www.nature.com/articles/s41591-020-0751-5
Testosterone supplementation is commonly used for its effects on sexual function, bone health and body composition, yet its effects on disease outcomes are unknown. To better understand this, we identified genetic determinants of testosterone levels and related sex hormone traits in 425,097 UK Biobank study participants. Using 2,571 genome-wide significant associations, we demonstrate that the genetic determinants of testosterone levels are substantially different between sexes and that genetically higher testosterone is harmful for metabolic diseases in women but beneficial in men. For example, a genetically determined 1 s.d. higher testosterone increases the risks of type 2 diabetes (odds ratio (OR) = 1.37 (95% confidence interval (95% CI): 1.22–1.53)) and polycystic ovary syndrome (OR = 1.51 (95% CI: 1.33–1.72)) in women, but reduces type 2 diabetes risk in men (OR = 0.86 (95% CI: 0.76–0.98)). We also show adverse effects of higher testosterone on breast and endometrial cancers in women and prostate cancer in men. Our findings provide insights into the disease impacts of testosterone and highlight the importance of sex-specific genetic analyses.
Among women with a natural menopause, the risk of breast cancer was nearly 2.5-fold greater among current users of estrogen plus testosterone therapies (multivariate relative risk, 2.48; 95% confidence interval, 1.53-4.04) than among never users of PMHs
Consistent with the elevation in risk with increasing endogenous testosterone level, women using E&T therapies have a significantly increased risk of invasive breast cancer. These results are also consistent with studies showing that E&P therapies with synthetic testosterone-derived progestogens are associated with a greater risk of breast cancer compared with those with micronized progesterone.45 These results are especially important given the already apparent increase in trends and the expectation that more formulations containing testosterone will become specifically approved for and marketed to women.
https://jamanetwork.com/journals/jam...article/410682
High testosterone in women ups risk for cancer, diabetes, and metabolic disease
They revealed that women with genetically higher testosterone levels have a heightened risk of developing type 2 diabetes by 37 percent. On the other hand, men had a reduction of type 2 diabetes risk by 14 percent if they had higher testosterone levels.
The women also had a 51-percent increased risk of polycystic ovary syndrome (PCOS). PCOS was previously thought to have caused high testosterone levels.
Further, findings of the study unveiled that higher testosterone levels in women had been tied to a higher risk of developing cancer, including endometrial and breast cancer. In men, high levels of the hormone are linked to higher prostate cancer risk. The team concluded that there is a genetic component to testosterone levels in both sexes, but the effects were very different between men and women.
Using human genetics to understand the disease impacts of testosterone in men and women
https://www.nature.com/articles/s41591-020-0751-5
Testosterone supplementation is commonly used for its effects on sexual function, bone health and body composition, yet its effects on disease outcomes are unknown. To better understand this, we identified genetic determinants of testosterone levels and related sex hormone traits in 425,097 UK Biobank study participants. Using 2,571 genome-wide significant associations, we demonstrate that the genetic determinants of testosterone levels are substantially different between sexes and that genetically higher testosterone is harmful for metabolic diseases in women but beneficial in men. For example, a genetically determined 1 s.d. higher testosterone increases the risks of type 2 diabetes (odds ratio (OR) = 1.37 (95% confidence interval (95% CI): 1.22–1.53)) and polycystic ovary syndrome (OR = 1.51 (95% CI: 1.33–1.72)) in women, but reduces type 2 diabetes risk in men (OR = 0.86 (95% CI: 0.76–0.98)). We also show adverse effects of higher testosterone on breast and endometrial cancers in women and prostate cancer in men. Our findings provide insights into the disease impacts of testosterone and highlight the importance of sex-specific genetic analyses.
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03-05-2024, 05:58 PM
#792
Originally Posted By jtaylor2010⏩
Study after study shows the dangers, not to mention all the testimonials being put out of regret…must be good money in this racket..
He knows, but he just wants to troll. That’s why he says retarded things like “ The recommended serum levels of estradiol and testosterone are the same for those prescribed hormones for gender dysphoria as for those who are prescribed hormones for HRT.”
If a 40 year old female actually gets a competent provider who will give them care and oversee hormone therapy that involves testosterone, the dosage will be tiny and monitored closely for adverse effects. If a 20 year old female goes to her doctor and gets testosterone to “affirm her gender as male” she gets enough testosterone to start growing facial hair and all kinds of other sh!t, those two scenario aren’t even in the same ballpark with regard to what levels the doctors are “recommending” and the risk profile certainly isn’t the same either.
But again, he knows this and just wants to be obtuse.
If a 40 year old female actually gets a competent provider who will give them care and oversee hormone therapy that involves testosterone, the dosage will be tiny and monitored closely for adverse effects. If a 20 year old female goes to her doctor and gets testosterone to “affirm her gender as male” she gets enough testosterone to start growing facial hair and all kinds of other sh!t, those two scenario aren’t even in the same ballpark with regard to what levels the doctors are “recommending” and the risk profile certainly isn’t the same either.
But again, he knows this and just wants to be obtuse.
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03-05-2024, 05:59 PM
#793
Originally Posted By jtaylor2010⏩
Nicely done misrepresentation
He knows, but he just wants to troll. That’s why he says retarded things like “ The recommended serum levels of estradiol and testosterone are the same for those prescribed hormones for gender dysphoria as for those who are prescribed hormones for HRT.”
If a 40 year old female actually gets a competent provider who will give them care and oversee hormone therapy that involves testosterone, the dosage will be tiny and monitored closely for adverse effects. If a 20 year old female goes to her doctor and gets testosterone to “affirm her gender as male” she gets enough testosterone to start growing facial hair and all kinds of other sh!t, those two scenario aren’t even in the same ballpark with regard to what levels the doctors are “recommending” and the risk profile certainly isn’t the same either.
But again, he knows this and just wants to be obtuse.
If a 40 year old female actually gets a competent provider who will give them care and oversee hormone therapy that involves testosterone, the dosage will be tiny and monitored closely for adverse effects. If a 20 year old female goes to her doctor and gets testosterone to “affirm her gender as male” she gets enough testosterone to start growing facial hair and all kinds of other sh!t, those two scenario aren’t even in the same ballpark with regard to what levels the doctors are “recommending” and the risk profile certainly isn’t the same either.
But again, he knows this and just wants to be obtuse.
I said:
FTM will get similar test doses as biological men on TRT.
MTF will get similar estrogen doses as women on HRT.
Paul claimed the same doses are more harmful when used as GAHt than when used as TRT and HRT.
The summaries of trials posted above suggests that's untrue.
03-05-2024, 06:02 PM
#794
Originally Posted By Paul Kreul⏩
Cis people on HRT face the same risks.
Study after study shows the dangers, not to mention all the testimonials being put out of regret…must be good money in this racket..
Why should they be allowed to make that call but those with gender dysphoria not be allowed?
Are you really now trying to say you oppose GAHT due to the health risks for adults with gender dysphoria?
But you don't oppose TRT or HRT?
03-05-2024, 06:11 PM
#795
Originally Posted By J.L.C.⏩
Nicely done misrepresentation
I said:
FTM will get similar test doses as biological men on TRT.
MTF will get similar estrogen doses as women on HRT.
Paul claimed the same doses are more harmful when used as GAHt than when used as TRT and HRT.
The summaries of trials posted above suggests that's untrue.
I said:
FTM will get similar test doses as biological men on TRT.
MTF will get similar estrogen doses as women on HRT.
Paul claimed the same doses are more harmful when used as GAHt than when used as TRT and HRT.
The summaries of trials posted above suggests that's untrue.
Really?
So men lose the ability to have children and produce breast milk when on TRT..?
Source..?
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03-05-2024, 06:14 PM
#796
Originally Posted By Paul Kreul⏩
Imagine being so willing to troll that you’ll say giving a biological female enough testosterone to put her total level at 1,000 and giving a biological male enough to put his levels at 1,000 exposes the two individuals to the same amount of risk.
Study after study shows the dangers, not to mention all the testimonials being put out of regret…must be good money in this racket..
Seems like a weird way to spend(see also; waste) your time…but it’s his time so I guess he can do whatever he wants with it.
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03-05-2024, 06:15 PM
#797
Originally Posted By Paul Kreul⏩
Did you not see the tables above?
Really?
So men lose the ability to have children and produce breast milk when on TRT..?
Source..?
So men lose the ability to have children and produce breast milk when on TRT..?
Source..?
You didn't know TRT (at typical doses) affects fertility?
03-05-2024, 06:19 PM
#798
Originally Posted By J.L.C.⏩
In men, that's reversible..last I checked..men don't produce breast milk.
Did you not see the tables above?
You didn't know TRT affects fertility? But you're on it?
You didn't know TRT affects fertility? But you're on it?
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03-05-2024, 06:21 PM
#799
Originally Posted By jtaylor2010⏩
Men on TRT are shut down. Their serum test levels are from the ester.
Imagine being so willing to troll that you’ll say giving a biological female enough testosterone to put her total level at 1,000 and giving a biological male enough to put his levels at 1,000 exposes the two individuals to the same amount of risk.
Seems like a weird way to spend(see also; wasteh) your time…but it’s his time so I guess he can do whatever he wants with it.
Seems like a weird way to spend(see also; wasteh) your time…but it’s his time so I guess he can do whatever he wants with it.
Given that biological females tend to be smaller than biological males, biological females likely require lower doses to achieve similar serum levels.
It's replacement therapy, not top up therapy
03-05-2024, 06:23 PM
#800
Originally Posted By J.L.C.⏩
Lookin' pretty similar
Look up women being on testosterone, and what it does to them.
Lookin' pretty similar
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03-05-2024, 06:24 PM
#801
Originally Posted By J.L.C.⏩
Cis people???
Cis people on HRT face the same risks.
Why should they be allowed to make that call but those with gender dysphoria not be allowed?
Are you really now trying to say you oppose GAHT due to the health risks for adults with gender dysphoria?
But you don't oppose TRT or HRT?
Why should they be allowed to make that call but those with gender dysphoria not be allowed?
Are you really now trying to say you oppose GAHT due to the health risks for adults with gender dysphoria?
But you don't oppose TRT or HRT?
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03-05-2024, 06:25 PM
#802
Originally Posted By Dave22reborn⏩
First table shows the risk profile.
Look up women being on testosterone, and what it does to them.
03-05-2024, 06:25 PM
#803
Originally Posted By J.L.C.⏩
Men on TRT are shut down. Their serum test levels are from the ester.
Given that biological females tend to be smaller than biological males, biological females likely require lower doses to achieve similar serum levels.
It's replacement therapy, not top up therapy
Given that biological females tend to be smaller than biological males, biological females likely require lower doses to achieve similar serum levels.
It's replacement therapy, not top up therapy
You can still produce T while supplementing T…you do know this I hope..?
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03-05-2024, 06:25 PM
#804
Originally Posted By Dave22reborn⏩
Yeah, it's borrowed from organic chemistry.
Cis people???
03-05-2024, 06:26 PM
#805
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03-05-2024, 06:27 PM
#806
Originally Posted By Dave22reborn⏩
Not to mention, if a woman is receiving hormone therapy and goes in with levels elevated outside of the ranges for females the doctor will drop her dose down due to the risks associated with having levels outside of the range(much less getting up to around the higher levels of a biological male). But if she says she identifies as a male they’ll take her levels to the moon. How can a patient say magic words(like “I identify as a male”) that completely changes their risk profile?
Look up women being on testosterone, and what it does to them.
But again, and I feel like a broken record at this point….he realizes this and simply wants to troll.
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03-05-2024, 06:31 PM
#808
Originally Posted By jtaylor2010⏩
FTM people would be looking to have test levels similar to those of men on TRT. As mentioned above, it would likely require lower doses.
Not to mention, if a woman is receiving hormone therapy and goes in with levels elevated outside of the ranges for females the doctor will drop her dose down due to the risks associated with having levels outside of the range(much less getting up to around the higher levels of a biological male). But if she says she identifies as a male they’ll take her levels to the moon. How can a patient say magic words(like “I identify as a male”) that completely changes their risk profile?
But again, and I feel like a broken record at this point….he realizes this and simply wants to troll.
But again, and I feel like a broken record at this point….he realizes this and simply wants to troll.
Presumably, the physician prescribing and monitoring GAHT for a FTM patient would be aware of the recommended levels.
03-05-2024, 06:42 PM
#809
Originally Posted By J.L.C.⏩
That has Nothing to do with what the risk stated in women though..
Gyno is listed as a risk.
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