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Cortical thickness alterations and systemic inflammation with Long Covid
07-24-2023, 12:00 PM
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#1
Cortical thickness alterations and systemic inflammation with Long Covid
Cortical thickness alterations and systemic inflammation define long-COVID patients with cognitive impairment
"We identified distinct cortical areas showing a progressive increase in cortical thickness across different groups, starting from healthy individuals who had never been infected with COVID-19, followed by healthy COVID-19 survivors, long-COVID patients without cognitive deficits (MoCA ≥ 26), and finally, long-COVID patients exhibiting significant cognitive deficits (MoCA < 26).
These findings highlight the continuum of cortical thickness alterations associated with COVID-19, with more pronounced changes observed in individuals experiencing cognitive impairment (p<0.05, FWE-corrected). Affected cortical regions covered prefrontal and temporal gyri, insula, posterior cingulate, parahippocampal gyrus, and parietal areas.
Additionally, we discovered a distinct immunophenotype, with elevated levels of IL-10, IFNg, and sTREM2 in long-COVID patients, especially in the group suffering from cognitive impairment. We demonstrate lingering cortical and immunological alterations in healthy and impaired subgroups of COVID-19 survivors."
https://www.medrxiv.org/content/10.1....21.23292988v1
They used regression
Did not state funding
Declare no conflicts of interest

"We identified distinct cortical areas showing a progressive increase in cortical thickness across different groups, starting from healthy individuals who had never been infected with COVID-19, followed by healthy COVID-19 survivors, long-COVID patients without cognitive deficits (MoCA ≥ 26), and finally, long-COVID patients exhibiting significant cognitive deficits (MoCA < 26).
These findings highlight the continuum of cortical thickness alterations associated with COVID-19, with more pronounced changes observed in individuals experiencing cognitive impairment (p<0.05, FWE-corrected). Affected cortical regions covered prefrontal and temporal gyri, insula, posterior cingulate, parahippocampal gyrus, and parietal areas.
Additionally, we discovered a distinct immunophenotype, with elevated levels of IL-10, IFNg, and sTREM2 in long-COVID patients, especially in the group suffering from cognitive impairment. We demonstrate lingering cortical and immunological alterations in healthy and impaired subgroups of COVID-19 survivors."
https://www.medrxiv.org/content/10.1....21.23292988v1
They used regression
Did not state funding
Declare no conflicts of interest

07-24-2023, 12:07 PM
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#2
- Dave22reborn
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- Dave22reborn
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OMG, Am I gonna be okay???? I'm unvaccinated and had it twice!!!! Guess I should schedule numerous appoints for an MRI, go see a neurologist, maybe get a Cat scan, and God knows what else.......
07-24-2023, 12:10 PM
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#3
Originally Posted By Dave22reborn⏩
Cognitive impairment isn't necessarily life threatening.OMG, Am I gonna be okay???? I'm unvaccinated and had it twice!!!! Guess I should schedule numerous appoints for an MRI, go see a neurologist, maybe get a Cat scan, and God knows what else.......
As demonstrated in multiple studies, not everyone who gets covid experiences long covid or cognitive impairment.
07-24-2023, 12:25 PM
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#4
- Dave22reborn
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Originally Posted By J.L.C.⏩
I don't know, you've made numerous threads about this, maybe I should get checked out.......Cognitive impairment isn't necessarily life threatening.
As demonstrated in multiple studies, not everyone who gets covid experiences long covid or cognitive impairment.
As demonstrated in multiple studies, not everyone who gets covid experiences long covid or cognitive impairment.
07-24-2023, 12:27 PM
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#5
07-24-2023, 12:45 PM
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#6
- Dave22reborn
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Originally Posted By J.L.C.⏩
Who knows what damage I may have suffered......Checked out for what?
07-24-2023, 03:26 PM
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#7
07-24-2023, 03:49 PM
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#8
- sfgiants13
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R/zerocovid ——->
07-24-2023, 06:24 PM
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#9
- Fishman15
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Originally Posted By A-GAME⏩
^This, I'd be much more concerned with "Long Jab"...Lol @ long covid.
Hey Timmy, show us on the boy doll where the tampon goes...
07-24-2023, 06:38 PM
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#10
07-24-2023, 06:39 PM
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#11
- gachase21
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Originally Posted By J.L.C.⏩
Do you think it might be why George Floyd acted so combative and resistant in the beginning of the pandemic?Cognitive impairment isn't necessarily life threatening.
As demonstrated in multiple studies, not everyone who gets covid experiences long covid or cognitive impairment.
As demonstrated in multiple studies, not everyone who gets covid experiences long covid or cognitive impairment.
The possible stress also exacerbated his Covid caused heart issues?
07-24-2023, 06:46 PM
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#12
- Dave22reborn
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Originally Posted By gachase21⏩
Selfish ****, who knows how many people he infected for not being quarantined.Do you think it might be why George Floyd acted so combative and resistant in the beginning of the pandemic?
The possible stress also exacerbated his Covid caused heart issues?
The possible stress also exacerbated his Covid caused heart issues?
07-24-2023, 06:53 PM
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#13
07-24-2023, 06:54 PM
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#14
Originally Posted By gachase21⏩
********'s a helluva drugDo you think it might be why George Floyd acted so combative and resistant in the beginning of the pandemic?
The possible stress also exacerbated his Covid caused heart issues?
The possible stress also exacerbated his Covid caused heart issues?
07-24-2023, 07:07 PM
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#15
- jtaylor2010
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No peer review - check
Doesn’t appear to compare status of injected individuals vs. non-injected individuals - check
Concludes that unhealthy people are unhealthy - check
Used by J.ShiLL.C. to spam the forum with more “omg Covid is scary” threads - check
Doesn’t appear to compare status of injected individuals vs. non-injected individuals - check
Concludes that unhealthy people are unhealthy - check
Used by J.ShiLL.C. to spam the forum with more “omg Covid is scary” threads - check
07-24-2023, 07:16 PM
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#16
- Dave22reborn
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Originally Posted By J.L.C.⏩
He had the Rona. Why was he outside?2 month quarantine?
07-24-2023, 07:33 PM
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#17
- nkiritsis13
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So, is Long Covid when someone obsesses over a cough that even regular covidiots don't give a damn about anymore?


I will stand firm, I refuse to kneel - The fury in me is divine
My dark grave awaits, my fate is revealed - But I'm not afraid to die
If you have any problems or need advice, feel free to ask
07-24-2023, 07:36 PM
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#18
07-24-2023, 07:39 PM
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#19
07-24-2023, 07:44 PM
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#20
07-24-2023, 08:01 PM
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#21
- LeftistGent
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Stop posting chitty preprints bro
Anti identity politics crew
Anti corporate welfare crew
Anti federal reserve crew
Anti central banking cartel crew
ETH millionaire crew
07-24-2023, 08:05 PM
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#22
07-24-2023, 08:10 PM
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#23
- Paul Kreul
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OP is the one that is hired to go into forums and post about “long Covid” while the destruction of the jabs that were ushered out sets in.
I guess it makes sense now.
Everything he posts about will be the result of the CV jab
Watch and see.
I guess it makes sense now.
Everything he posts about will be the result of the CV jab
Watch and see.
07-24-2023, 08:11 PM
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#24
Originally Posted By Paul
But these effects are seen in unvaccinated peopleOP is the one that is hired to go into forums and post about “long Covid” while the destruction of the jabs that were ushered out sets in.
I guess it makes sense now.
Everything he posts about will be the result of the CV jab
Watch and see.
I guess it makes sense now.
Everything he posts about will be the result of the CV jab
Watch and see.

07-24-2023, 08:12 PM
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#25
- Paul Kreul
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Originally Posted By J.L.C.⏩
I’m sure. I trust all the studies you post. We all do broBut these effects are seen in unvaccinated people


07-24-2023, 08:15 PM
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#26
07-24-2023, 08:16 PM
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#27
- Paul Kreul
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Originally Posted By J.L.C.⏩
No really, everyone trusts you. Don’t doubt yourselfI think you're mixing that up a bit

07-24-2023, 08:17 PM
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#28
07-24-2023, 08:19 PM
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#29
- Paul Kreul
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Originally Posted By J.L.C.⏩
And I’m sure they are completely trustworthy. Just like the ties we saw with the last studu you posted.I'm not asking anyone to trust me or anything else. These papers are open access


07-24-2023, 08:26 PM
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#30
Brain microstructural changes and fatigue after COVID-19
https://www.frontiersin.org/articles...2.1029302/full
Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection
Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection
https://www.frontiersin.org/articles...2.1029302/full
Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection
Brain imaging and neuropsychological assessment of individuals recovered from a mild to moderate SARS-CoV-2 infection
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