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Hybrid Immunity Helpful for Immunocompromised Folks
07-17-2023, 03:35 PM
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#1
Hybrid Immunity Helpful for Immunocompromised Folks
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states
"Regardless of underlying immunodeficiency, booster-vaccinated and Omicron-infected individuals appeared protected against severe disease and exhibited enhanced and diversified T cell responses against conserved and Omicron-specific epitopes. Our findings indicate that T cells retain the ability to generate highly functional responses against newly emerging variants, even after repeated antigen exposure and a robust immunological imprint from ancestral SARS-CoV-2 mRNA vaccination."
https://www.science.org/doi/10.1126/...nslmed.adg9452
"Regardless of underlying immunodeficiency, booster-vaccinated and Omicron-infected individuals appeared protected against severe disease and exhibited enhanced and diversified T cell responses against conserved and Omicron-specific epitopes. Our findings indicate that T cells retain the ability to generate highly functional responses against newly emerging variants, even after repeated antigen exposure and a robust immunological imprint from ancestral SARS-CoV-2 mRNA vaccination."
https://www.science.org/doi/10.1126/...nslmed.adg9452
07-17-2023, 03:49 PM
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#2
07-17-2023, 03:52 PM
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#3
07-17-2023, 03:55 PM
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#4
- gachase21
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For those who may ask
Funding: This study has been funded by grants from the SciLifeLab National COVID-19 Research Program and financed by the Knut and Alice Wallenberg Foundation, the Swedish Research Council, Nordstjernan AB, Region Stockholm (Clinical research position-, ALF-, and CIMEDgrants), and a graduate student fellowship from Karolinska Institutet. In addition, the Swedish patient organizations of Primary Immunodeficiencies (PIO) and Hematology (Swedish Blood Cancer Foundation) provided grants. T.R.M. was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation)—496946670. T.S. was funded by the Swedish Research Council and Jeanssons Stiftelse. J.N. was supported by an EMBO postdoctoral fellowship (ALTF 1062-2020) and an SSMF postdoctoral grant. A.C.K. was supported by the Swedish Research Council (Dnr: 2020-02033); CIMED project grant, senior (Dnr: 20190495); and Karolinska Institutet (Dnr: 2019-00931 and 2020-01599). S.K.S. is funded by the Danish Cancer Society R306-A18139. S.A. was supported by the Swedish Research Council, the Knut and Alice Wallenberg Foundation, and CIMED from Karolinska Institutet. M.B. was supported by the Swedish Research Council (2018-02330, 2020-06121, and 2021-04779), the Knut and Alice Wallenberg Foundation (KAW 2021.0136), the European Research Council (101057129 and 101041484), Karolinska Institutet (2019-00969), the Swedish Society for Medical Research (CG-22-0009), the Swedish Cancer Society (22 2237 Pj), the Åke Wibergs Stiftelse (M20-0190), and the Jonas Söderquist Stiftelse.
Author contributions: T.R.M., T.S., J.N., A.C.K., H.-G.L., S.A., and M.B. conceptualized the study. T.R.M., T.S., and J.N. performed AIM and functional assays. D.T. and S.P.A.H. performed epitope mapping experiments. Formal analysis was performed by T.R.M., T.S., D.T., and J.N. T.R.M. visualized data. T.R.M., T.S., J.N., P.C., P.B., O.B., L.H., S.M., P.N., J.V., M.A., A.O., Y.G., C.C., G.S., C.I.E.S., A.Ö., K.L., M.S.C., P.L., H.-G.L., A.C.K., S.K.S., S.A., and M.B. were involved in sample collection and resource provision. H.-G.L., A.C.K., S.K.S., S.A., and M.B. acquired funding for this study. H.-G.L., A.C.K., S.K.S., and M.B. supervised research. The manuscript was originally written and edited by T.R.M. and M.B. All authors reviewed and edited revisions of the manuscript and had final responsibility for the decision to submit for publication.
Competing interests: M.B. is a consultant and has received honoraria from Oxford Immunotec, MSD, BMS, Pfizer, and Mabtech.S.A. has received honoraria for lectures and educational events, not related to this work, from Gilead, AbbVie, MSD, and Biogen, and reports grants from Gilead and AbbVie. The other authors declare that they have no competing interests.
Author contributions: T.R.M., T.S., J.N., A.C.K., H.-G.L., S.A., and M.B. conceptualized the study. T.R.M., T.S., and J.N. performed AIM and functional assays. D.T. and S.P.A.H. performed epitope mapping experiments. Formal analysis was performed by T.R.M., T.S., D.T., and J.N. T.R.M. visualized data. T.R.M., T.S., J.N., P.C., P.B., O.B., L.H., S.M., P.N., J.V., M.A., A.O., Y.G., C.C., G.S., C.I.E.S., A.Ö., K.L., M.S.C., P.L., H.-G.L., A.C.K., S.K.S., S.A., and M.B. were involved in sample collection and resource provision. H.-G.L., A.C.K., S.K.S., S.A., and M.B. acquired funding for this study. H.-G.L., A.C.K., S.K.S., and M.B. supervised research. The manuscript was originally written and edited by T.R.M. and M.B. All authors reviewed and edited revisions of the manuscript and had final responsibility for the decision to submit for publication.
Competing interests: M.B. is a consultant and has received honoraria from Oxford Immunotec, MSD, BMS, Pfizer, and Mabtech.S.A. has received honoraria for lectures and educational events, not related to this work, from Gilead, AbbVie, MSD, and Biogen, and reports grants from Gilead and AbbVie. The other authors declare that they have no competing interests.
An honorarium is any payment made in exchange for rendering a service or activity that is not part of your official duties. Examples include: delivering a speech, writing or publishing an article, or participating in a public or private conference, convention, meeting, or similar event.
An honorarium is a payment for services for which custom or propriety forbids a price to be set. This method of payment is usually made to a guest speaker or lecturer as a "thank you" and gesture of good will and appreciation.
07-17-2023, 04:04 PM
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07-17-2023, 04:11 PM
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#6
07-17-2023, 04:17 PM
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#7
07-17-2023, 04:38 PM
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#8
- chicagopizzaboy
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- chicagopizzaboy
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Why are you pushing shots which have already killed hundreds of thousands in the US and crippled up millions more? Someone might read your murderous misinformation and actually harm themselves. How can you sleep at night? You POS.
Prestigious British Medical Journal (BMJ) Says COVID Vaccines Are 20 Times More Dangerous Than COVID
https://jme.bmj.com/content/early/20...me-2022-108449
https://thewashingtonstandard.com/sh...g-covid-shots/

CENSORED VACCINE INJURY AND DEATH INFORMATION SITES
Search Twitter by
Real Not Rare.
Real Not Rare******** page.
REACT19.Org
CanWeTalkAboutIt.org
“Anecdotals”(documentary)
“Safe and Effective”(documentary)
The Vaccine Reaction
Children’s Health Defense
World Council for Health: Covid-19 Vaccine Pharmacovigilance Report
1,000+ Peer Reviewed Articles On COVID Vaccine Injuries
Reuters: COVID Vaccine Injury Claims Skyrocket 16-Fold to 5400
Links to doctors’ calls for halts to mass “vaccinations,” partial list:1,2,3,4,5.
Prestigious British Medical Journal (BMJ) Says COVID Vaccines Are 20 Times More Dangerous Than COVID
https://jme.bmj.com/content/early/20...me-2022-108449
mRNA shots (made by Pfizer and Moderna) are “likely to cause net expected harms to young healthy adults—for each hospitalisation averted we estimate approximately [18.5 serious adverse events]…“
Columbia University Professor Estimates Up to 400,000 dead from COVID End of 2021https://thewashingtonstandard.com/sh...g-covid-shots/

CENSORED VACCINE INJURY AND DEATH INFORMATION SITES
Search Twitter by
and
Real Not Rare.
Real Not Rare******** page.
REACT19.Org
CanWeTalkAboutIt.org
“Anecdotals”(documentary)
“Safe and Effective”(documentary)
The Vaccine Reaction
Children’s Health Defense
World Council for Health: Covid-19 Vaccine Pharmacovigilance Report
1,000+ Peer Reviewed Articles On COVID Vaccine Injuries
Reuters: COVID Vaccine Injury Claims Skyrocket 16-Fold to 5400
Links to doctors’ calls for halts to mass “vaccinations,” partial list:1,2,3,4,5.
Who is J6 "Scaffold Commander," the key to the J6 Fedsurrection? https://rumble.com/v45y4z6-why-is-the-king-pin-of-j6-scaffold-commander-not-wanted-nor-identified-by-t.html
07-17-2023, 04:41 PM
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07-17-2023, 05:04 PM
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#10
07-17-2023, 05:30 PM
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#11
07-17-2023, 05:32 PM
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#12
Originally Posted By Anachron⏩
A science sub would be coolSubconsciously, even Slow Creep admits that he's posting because he considers the topic political, not science related.
Or even better, something that could be considered a religion ( the sacred Rona ).
Or even better, something that could be considered a religion ( the sacred Rona ).


07-17-2023, 05:34 PM
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#13
07-17-2023, 05:35 PM
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#14
Originally Posted By Anachron⏩
You can always report my posts/threadsThere's the main misc, you don't have to spam threads that have nothing to do with politics or religion in R&P.
Or I was right, and you consider Covid related topics to be political and/or religious.
Or I was right, and you consider Covid related topics to be political and/or religious.


07-17-2023, 05:38 PM
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#15
07-17-2023, 05:40 PM
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#16
Originally Posted By Anachron⏩
If that's how you choose to participate on this forum, I'm cool with it. You do youI don't have to.
It's enough for me to know that you consider each and every thread you make in this subsection to be either political or religious in nature.
Do you consider the topic of this thread political or religious?
It's enough for me to know that you consider each and every thread you make in this subsection to be either political or religious in nature.
Do you consider the topic of this thread political or religious?


07-17-2023, 05:41 PM
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#17
07-17-2023, 05:43 PM
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#18
07-17-2023, 05:50 PM
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#19
Originally Posted By Anachron⏩
Ono. We didn't have the cool sounding tech you imagine. I'm in CanadaDid the individual syringes for those come with labels that had drop down menus, just like how according to you, the Pfizer ones did?


07-17-2023, 05:57 PM
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#20
Originally Posted By Anachron⏩
Nah.Are you telling me you made up a story about the drop-down menus on the labels of the individual syringes?
How disappointing, but par for the course.
I guess since what you claimed doesn't exist, neither does lot control of the vaccines in the beavercel medical system.
How disappointing, but par for the course.
I guess since what you claimed doesn't exist, neither does lot control of the vaccines in the beavercel medical system.

None of that is true
But, I respect your right to read, not read, criticize and/or judge anything I post. I also don't care

07-17-2023, 06:01 PM
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#21
Originally Posted By Anachron⏩
If you have more, or better detailed, info on how covid vaccine clinics were run in Ontario, I'm all earsI wonder why someone who claims to have been administering these vaccines doesn't know how the lots were controlled from vial to injection.


07-17-2023, 06:30 PM
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#22
07-18-2023, 05:24 AM
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#23
- Dave22reborn
- Cold Hearted SOB
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- Dave22reborn
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Gonna be 2024 real soon, and OP is telling us to "Be afraid, be very afraid."
07-18-2023, 05:27 AM
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#24
- jtaylor2010
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Originally Posted By Dave22reborn⏩
He’ll never officially recommend anything, but keeps putting out “studies” and saying they’re “good news” if they show any type of benefit for the injections. Just lol….he never met a vaccine he didn’t love.Gonna be 2024 real soon, and OP is telling us to "Be afraid, be very afraid."
07-18-2023, 06:01 AM
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#25
07-18-2023, 06:02 AM
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#26
Originally Posted By jtaylor2010⏩
But this one used unsupervised learningHe’ll never officially recommend anything, but keeps putting out “studies” and saying they’re “good news” if they show any type of benefit for the injections. Just lol….he never met a vaccine he didn’t love.

07-18-2023, 06:05 AM
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#27
07-18-2023, 06:08 AM
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#28
- Cleveland33
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- Cleveland33
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as someone who is immunocompromised and unvaxxed is there any advantage to me getting vaxxed?
07-18-2023, 06:10 AM
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#29
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