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SARS-CoV-2 reservoir in post-acute sequelae of COVID-19
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09-04-2023, 03:16 PM
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#1
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
"Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19 (PASC).
Several biological factors have emerged as potential drivers of PASC pathology. Some individuals with PASC may not fully clear the coronavirus SARS-CoV-2 after acute infection. Instead, replicating virus and/or viral RNA—potentially capable of being translated to produce viral proteins—persist in tissue as a ‘reservoir’.
This reservoir could modulate host immune responses or release viral proteins into the circulation. Here we review studies that have identified SARS-CoV-2 RNA/protein or immune responses indicative of a SARS-CoV-2 reservoir in PASC samples. Mechanisms by which a SARS-CoV-2 reservoir may contribute to PASC pathology, including coagulation, microbiome and neuroimmune abnormalities, are delineated.
We identify research priorities to guide the further study of a SARS-CoV-2 reservoir in PASC, with the goal that clinical trials of antivirals or other therapeutics with potential to clear a SARS-CoV-2 reservoir are accelerated."
https://www.nature.com/articles/s41590-023-01601-2
"Millions of people are suffering from Long COVID or post-acute sequelae of COVID-19 (PASC).
Several biological factors have emerged as potential drivers of PASC pathology. Some individuals with PASC may not fully clear the coronavirus SARS-CoV-2 after acute infection. Instead, replicating virus and/or viral RNA—potentially capable of being translated to produce viral proteins—persist in tissue as a ‘reservoir’.
This reservoir could modulate host immune responses or release viral proteins into the circulation. Here we review studies that have identified SARS-CoV-2 RNA/protein or immune responses indicative of a SARS-CoV-2 reservoir in PASC samples. Mechanisms by which a SARS-CoV-2 reservoir may contribute to PASC pathology, including coagulation, microbiome and neuroimmune abnormalities, are delineated.
We identify research priorities to guide the further study of a SARS-CoV-2 reservoir in PASC, with the goal that clinical trials of antivirals or other therapeutics with potential to clear a SARS-CoV-2 reservoir are accelerated."
https://www.nature.com/articles/s41590-023-01601-2
09-04-2023, 03:21 PM
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#2
09-04-2023, 06:35 PM
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#3
- Bushmaster
- Masculine Toxicity
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- Bushmaster
- Masculine Toxicity
- Join Date: Jul 2003
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...
Originally Posted By Bushmaster⏩
Oh look... another J.F.C covid worship thread. This is new and original.


It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
09-04-2023, 06:39 PM
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#4
- Bushmaster
- Masculine Toxicity
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- Bushmaster
- Masculine Toxicity
- Join Date: Jul 2003
- Location: Greenville, South Carolina, United States
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Multiple covid worship threads on the daily.. one after another...

Originally Posted By Bushmaster⏩
It's amazing... You act THIS fuking stupid, yet you still expect everybody to take you and your covid addiction seriously.

Originally Posted By J.L.C.⏩
What makes you think I expect anyone on the misc to take me seriously?
Originally Posted By Bushmaster⏩
Want me to count up the number of covid threads you've made in the past couple of weeks?
Originally Posted By J.L.C.⏩
But he doesn't want anybody to take him seriously.Wat?

It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
09-04-2023, 07:07 PM
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#5
- Dave22reborn
- Cold Hearted SOB
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- Dave22reborn
- Cold Hearted SOB
- Join Date: Jan 2005
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Get Covid, claim you're suffering "Long Covid" collect disability?
09-04-2023, 07:18 PM
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#6
09-04-2023, 07:26 PM
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#7
09-04-2023, 07:40 PM
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#8
- sfgiants13
- Էպշտեյնը իրեն չսպանեց
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- sfgiants13
- Էպշտեյնը իրեն չսպանեց
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- Location: Seattle, Washington, United States
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Reddit———>
09-04-2023, 07:41 PM
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#9
09-04-2023, 07:50 PM
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#10
- sfgiants13
- Էպշտեյնը իրեն չսպանեց
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- sfgiants13
- Էպշտեյնը իրեն չսպանեց
- Join Date: Feb 2003
- Location: Seattle, Washington, United States
- Posts: 12,532
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Originally Posted By J.L.C.⏩
It’s that wayHow is it?
09-05-2023, 05:05 AM
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#11
- Bushmaster
- Masculine Toxicity
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- Bushmaster
- Masculine Toxicity
- Join Date: Jul 2003
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Originally Posted By XterraRob⏩
CovidJLC, what is the person like that's behind your username?
What are some of your favorite hobbies?
What are some of your favorite hobbies?
Originally Posted By J.L.C.⏩
Don't flatter yourself. Ridiculing you and your covid addiction is not stalking.Ask my post stalkers
This thread 'bout PASC

This thread 'bout PASC
It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
09-05-2023, 05:11 AM
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#12
- jtaylor2010
- Join Date: Mar 2010
- Location: United States
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Thus the recent shrieking is a true grass-roots (or maybe more accurately Twitter-roots) phenomenon.
At its heart is a small but loud group of very online folks who cannot stand the fact that the world has moved on from Covid. They feel increasingly ostracized over their mask-wearing, whining about ventilation, and demands for never-ending free tests and vaccines.
In reality, almost no one cares enough to judge them, a fact that bothers them even more.
Even worse, many of them are “disabled” as a result of “long Covid” and do not work, giving them even more time to wind each other up. Since 2021, they have desperately hoped for validation for long Covid.
But the $1 billion long Covid research slush fund they convinced the National Institutes of Health to set up is almost gone, with no signs of progress. (It’s hard to solve a disease that exists mostly entirely in the minds of its sufferers when the first rule of research is pretending the disease isn’t ****tic.)
For the long Covidians, illness is ideology - as well as a pocketbook issue. The murkier long Covid is as an illness, the more resistance their disability applications will face.
No accident, then, that the recent warnings often prominently feature the \dangers of long Covid. (Highlighting long Covid also helps gloss over the mildness of Covid itself, a crucial step given that almost everyone has now had the virus and can no longer be terrified with tales of blood clots and sudden death.)
—
Meanwhile, though Democratic politicians want nothing to do with Covid 2.0 (3.0?) , their usual allies in the elite media have proven only too willing to amplify the recent Twitter freakouts.
After all, the Times and similar woke outlets don’t have elections to win. They cater to an increasingly narrow slice of the population that includes essentially everyone who is predisposed to believe the worst about long Covid. Not a few of their writers are long Covidians too.
And so the Times, CNN, and the rest have all dutifully reported on the new wave. They haven’t forgotten to mention long Covid, either.
“Every time you get infected, no matter the severity, there is always a chance that you can develop longer-term symptoms,” the Times wrote today in a story about reinfections.
As for what they want?
They want what they’ve wanted from the start of Covid. They want what they always want. They want everyone to be scared. They want free stuff.
Most of all, they want you to listen.
And obey.
At its heart is a small but loud group of very online folks who cannot stand the fact that the world has moved on from Covid. They feel increasingly ostracized over their mask-wearing, whining about ventilation, and demands for never-ending free tests and vaccines.
In reality, almost no one cares enough to judge them, a fact that bothers them even more.
Even worse, many of them are “disabled” as a result of “long Covid” and do not work, giving them even more time to wind each other up. Since 2021, they have desperately hoped for validation for long Covid.
But the $1 billion long Covid research slush fund they convinced the National Institutes of Health to set up is almost gone, with no signs of progress. (It’s hard to solve a disease that exists mostly entirely in the minds of its sufferers when the first rule of research is pretending the disease isn’t ****tic.)
For the long Covidians, illness is ideology - as well as a pocketbook issue. The murkier long Covid is as an illness, the more resistance their disability applications will face.
No accident, then, that the recent warnings often prominently feature the \dangers of long Covid. (Highlighting long Covid also helps gloss over the mildness of Covid itself, a crucial step given that almost everyone has now had the virus and can no longer be terrified with tales of blood clots and sudden death.)
—
Meanwhile, though Democratic politicians want nothing to do with Covid 2.0 (3.0?) , their usual allies in the elite media have proven only too willing to amplify the recent Twitter freakouts.
After all, the Times and similar woke outlets don’t have elections to win. They cater to an increasingly narrow slice of the population that includes essentially everyone who is predisposed to believe the worst about long Covid. Not a few of their writers are long Covidians too.
And so the Times, CNN, and the rest have all dutifully reported on the new wave. They haven’t forgotten to mention long Covid, either.
“Every time you get infected, no matter the severity, there is always a chance that you can develop longer-term symptoms,” the Times wrote today in a story about reinfections.
As for what they want?
They want what they’ve wanted from the start of Covid. They want what they always want. They want everyone to be scared. They want free stuff.
Most of all, they want you to listen.
And obey.
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