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Forum » Covid and post exercise malaise
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Thread: Covid and post exercise malaise

post 1695868253 01-04-2024, 03:31 PM
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Covid and post exercise malaise

Muscle abnormalities worsen after post-exertional malaise in long COVID

"We show that skeletal muscle structure is associated with a lower exercise capacity in patients, and local and systemic metabolic disturbances, severe exercise-induced myopathy and tissue infiltration of amyloid-containing deposits in skeletal muscles of patients with long COVID worsen after induction of post-exertional malaise. This study highlights novel pathways that help to understand the pathophysiology of post-exertional malaise in patients suffering from long COVID and other post-infectious diseases."

"The authors declare no competing interests."

"This study was funded by own funding, the Patient-Led Research Collaborative for Long COVID (Grant ID: C1, [MvV]), the Talud Foundation for the Amsterdam UMC Corona Research Fund [WWJ], AMC Foundation [MvV], VU Foundation [RCIW], ZonMw Onderzoeksprogramma ME/CVS [RCIW], and the 2022 Ramsay Grant Program [RCIW]."

All data and code are available

Vaccination balanced between groups

https://www.nature.com/articles/s41467-023-44432-3
post 1695868593 01-04-2024, 03:39 PM
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This is why I’m so tired all the time
Superight Crew
AntiVaxx Cew
COVID is a jok Crew
post 1695869013 01-04-2024, 03:48 PM
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This study is observational in nature, and therefore we cannot establish causality. We only included individuals with severe long COVID


In conclusion, this study reveals that local and systemic metabolic disturbances, severe exercise-induced myopathy, infiltration of amyloid-containing deposits, and immune cells in skeletal muscles of long COVID are key characteristics of post-exertional malaise.While these explain the symptomatology of post-exertional malaise in long COVID, the molecular pathways underlying these alterations in patients suffering from post-exertional malaise remain to be determined.





When you read it, were you thinking “I refuse to accept this if they can’t name the mechanism of action!”? Just wondering because I’ve seen you take that approach before.
post 1695869293 01-04-2024, 03:53 PM
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Originally Posted By jtaylor2010⏩
This study is observational in nature, and therefore we cannot establish causality. We only included individuals with severe long COVID


In conclusion, this study reveals that local and systemic metabolic disturbances, severe exercise-induced myopathy, infiltration of amyloid-containing deposits, and immune cells in skeletal muscles of long COVID are key characteristics of post-exertional malaise.While these explain the symptomatology of post-exertional malaise in long COVID, the molecular pathways underlying these alterations in patients suffering from post-exertional malaise remain to be determined.





When you read it, were you thinking “I refuse to accept this if they can’t name the mechanism of action!”? Just wondering because I’ve seen you take that approach before.
Your approach to review is truly hilarious.

But, I can fully understand why you don't like the results.

post 1695871153 01-04-2024, 04:29 PM
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Originally Posted By J.L.C.⏩
Covid
You really really love it, don't you.
It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
post 1695872753 01-04-2024, 04:55 PM
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Originally Posted By Bushmaster⏩
You really really love it, don't you.
Gives his life meaning.
post 1695873553 01-04-2024, 05:09 PM
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  1. Dave22reborn
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Probably had it three times OP, am I gonna be okay?
post 1695873653 01-04-2024, 05:11 PM
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So Covid will give you brain damage, high blood pressure, high cholesterol, make you impotent, give you diabetes, make you schizophrenic, and now give you post exercise malaise???

I'm sure I left out a whole bunch of other side effects.
post 1695873773 01-04-2024, 05:14 PM
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Originally Posted By Dave22reborn⏩
So Covid will give you brain damage, high blood pressure, high cholesterol, make you impotent, give you diabetes, make you schizophrenic, and now give you post exercise malaise???

I'm sure I left out a whole bunch of other side effects.
Change "will" to "can" and you're aligned with current evidence
post 1695873793 01-04-2024, 05:14 PM
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I have long Covid
Ack...Ack
post 1695874293 01-04-2024, 05:23 PM
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Originally Posted By EarlA⏩
I have long Covid
I have thick covid.
It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
post 1695875723 01-04-2024, 05:50 PM
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Originally Posted By EarlA⏩
I have long Covid
I’m gay
Superight Crew
AntiVaxx Cew
COVID is a jok Crew
post 1695880583 01-04-2024, 07:17 PM
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Originally Posted By J.L.C.⏩
Change "will" to "can" and you're aligned with current evidence
Remember you claiming that hundreds of millions might be suffering from "Long Covid?"
post 1695880663 01-04-2024, 07:18 PM
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Originally Posted By Dave22reborn⏩
Remember you claiming that hundreds of millions might be suffering from "Long Covid?"
Nope. Do you have a quote?
post 1695892083 01-04-2024, 11:52 PM
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OP needs to post this because we see the real world effects of the jab. OP is paid to run disinformation regarding the jab and have people believe it is "covid/long covid". No really...that's his schtick..click on his name and look at his post history
post 1695892443 01-05-2024, 12:05 AM
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There are now over 500 viruses strongly associated with Alzheimer's and Parkinson's development. SARS2 uniquely bad doh, huh? LOL. OP is unaware that every panic he has about SARS2 also applies to when people have a bad case of the flu.

Don't be very fat (a superspreader of all viruses) don't drink soda. High loads of sugar are great at creating gut permeability, damage that extends well beyond the limited world of viruses. This is barely scratching the surface of everyday stuff most people are damaging themselves with. Viruses are the cherry on top.
Yeah Buddyyy! Light weight! Light weight baby!!!!
post 1695897373 01-05-2024, 05:16 AM
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Originally Posted By frankdtank20⏩
There are now over 500 viruses strongly associated with Alzheimer's and Parkinson's development. SARS2 uniquely bad doh, huh? LOL. OP is unaware that every panic he has about SARS2 also applies to when people have a bad case of the flu.

Don't be very fat (a superspreader of all viruses) don't drink soda. High loads of sugar are great at creating gut permeability, damage that extends well beyond the limited world of viruses. This is barely scratching the surface of everyday stuff most people are damaging themselves with. Viruses are the cherry on top.
I trust you, bro.

But, what do you think of this study? Longitudinal case-control with matching by BMI and clearly not everyone was fat (mean BMI ~24).
post 1695897633 01-05-2024, 05:26 AM
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The only people buying this here (Pat, OP, wincel, Zcuck) don’t exercise anyway.

Back to Reddit
post 1695897733 01-05-2024, 05:30 AM
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They say long Covid makes you more susceptible to the heebie jeebies.
Ack...Ack
post 1695902303 01-05-2024, 07:21 AM
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Originally Posted By EarlA⏩
They say long Covid makes you more susceptible to the heebie jeebies.
Yikes!
post 1695902373 01-05-2024, 07:23 AM
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#21
  1. Bushmaster
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Originally Posted By EarlA⏩
They say long Covid makes you more susceptible to the heebie jeebies.
It made a crack in my windshield.
It's a hot night. The mind races. You think about your knife: the only friend who hasn't betrayed you, the only friend who won't be dead by sunup. Sleep tight mates, in your quilted chambray night shirts.
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