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Trust the Science: EXPERTS in the AAP, "Give kids Ozempic!"
02-04-2024, 05:25 PM
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#121
- Dave22reborn
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- Dave22reborn
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Originally Posted By J.L.C.⏩
Right, just like it was an option flr morbidly obese adults..... How'd that turn out?You have options if you don't like what I post
This thread is about OP being upset that Ozempic has been approved as an option for morbidly obese teens.
I shared the source material on the trials and FDA decision

This thread is about OP being upset that Ozempic has been approved as an option for morbidly obese teens.
I shared the source material on the trials and FDA decision

What is with you and this mindset of medication or an injection being the solution to a problem???
02-04-2024, 05:25 PM
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#122
Originally Posted By JUSA⏩
Dunno. Maybe you're just "shilling"Why do you keep saying I am upset?

Originally Posted By JUSA⏩
https://www.theatlantic.com/health/a...-risks/674204/
Semaglutide is the active ingredient in Wegovy, Ozempic, and Rybelsus. AAP = American Academy of Pediatrics i.e. Experts and infallible, can not be wrong and you can not question them.
DO NOT BE ALARMED
The FDA has *Approved* Ozempic for both Adults and Teens!!! IT'S SAFE!
FDA approves high-dose semaglutide for adolescents with obesity
https://diabetes.medicinematters.com...esity/23902216
Please, give your developing children Ozempic. Take it yourself. Everyone must take Ozempic. Consume. It's FDA approved, that means: We know it is safe! Just cherish we live in the United States of America, one of the few countries that allow it.
Ignore anti-science CTards who talk about it fuking up people's guts or doing permanent damage and that people regain weight when they're off. The FDA has spoken: It's safe and CTards should be in prison for spreading misinformation. It should not be legal to question the FDA, AAP or The Science.
Semaglutide is the active ingredient in Wegovy, Ozempic, and Rybelsus. AAP = American Academy of Pediatrics i.e. Experts and infallible, can not be wrong and you can not question them.
DO NOT BE ALARMED
The FDA has *Approved* Ozempic for both Adults and Teens!!! IT'S SAFE!
FDA approves high-dose semaglutide for adolescents with obesity
https://diabetes.medicinematters.com...esity/23902216
Please, give your developing children Ozempic. Take it yourself. Everyone must take Ozempic. Consume. It's FDA approved, that means: We know it is safe! Just cherish we live in the United States of America, one of the few countries that allow it.
Ignore anti-science CTards who talk about it fuking up people's guts or doing permanent damage and that people regain weight when they're off. The FDA has spoken: It's safe and CTards should be in prison for spreading misinformation. It should not be legal to question the FDA, AAP or The Science.
02-04-2024, 05:40 PM
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#123
- Dave22reborn
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Originally Posted By J.L.C.⏩
You didnt even know about any of the negative side effects of Ozempic, but here you are, praising it like your precious Covid jab.....Dunno. Maybe you're just "shilling"

02-04-2024, 06:02 PM
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#124
Originally Posted By Dave22reborn⏩
What makes you think I wasn't aware of some effects?You didnt even know about any of the negative side effects of Ozempic, but here you are, praising it like your precious Covid jab.....
What makes you think I'm "praising" anything?
OP got mad.
I shared source material.

02-04-2024, 06:36 PM
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#125
- Paul Kreul
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Originally Posted By J.L.C.⏩
Why didn't you post any negative effects then?What makes you think I wasn't aware of some effects?
What makes you think I'm "praising" anything?
OP got mad.
I shared source material.

What makes you think I'm "praising" anything?
OP got mad.
I shared source material.

02-04-2024, 07:10 PM
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#126
- Dave22reborn
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Originally Posted By J.L.C.⏩
Probably because you didn't even know about the loss of bone density or muscle mass, or numerous other side effects, even though this has been known for years.....What makes you think I wasn't aware of some effects?
What makes you think I'm "praising" anything?
OP got mad.
I shared source material.

What makes you think I'm "praising" anything?
OP got mad.
I shared source material.

02-04-2024, 07:17 PM
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#127
- z4v4
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Originally Posted By JUSA⏩
These people:Who? I mean, type 2 is directly a result of diet/lifestyle. Someone may have a genetic disposition to be more inclined to get it, but bad diets will always be at the root of it.
Originally Posted By JUSA⏩
The problem, greedy executives saw that a side-effect was massive weight loss - and here we are.
Deepfat: "I guarantee I beat you by at least 6 strokes. Afterwards, I'll slide my thick conservative cawk in your old lady just to finish the job."
z4: "So when are you available in September to play?"
Deep: "On second thought, I don't play golf with broads. You're such a scumbag that I'd be much more inclined to just slap the chit out of you."
z4: "MMA match works, too. So when are you available this month?
Deep: "I won't subject myself to being in the presence of a scumbag."
02-04-2024, 07:17 PM
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#128
02-04-2024, 07:52 PM
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#129
- Paul Kreul
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Originally Posted By J.L.C.⏩
But you chose to disregard the negative facts, why?Wat?
I posted the registered trial, the protocol, and the pub.
I posted the registered trial, the protocol, and the pub.
02-04-2024, 07:54 PM
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#130
02-04-2024, 07:55 PM
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#131
02-04-2024, 07:57 PM
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#132
- Paul Kreul
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Originally Posted By J.L.C.⏩
post number you reference negative sides?I don't think that happened.
You in on the misc analysis jam?
You in on the misc analysis jam?
02-04-2024, 08:00 PM
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#133
02-04-2024, 08:02 PM
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#134
- Paul Kreul
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Originally Posted By J.L.C.⏩
oh okay..you just chose not to discuss that part of the trial results?Part of the trial results

02-04-2024, 08:04 PM
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#135
02-04-2024, 08:13 PM
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#136
- Paul Kreul
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Originally Posted By J.L.C.⏩
post number you reference negative sides?Which part did I discuss?

02-04-2024, 08:18 PM
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#137
Originally Posted By Paul
This is #16post number you reference negative sides?
Originally Posted By J.L.C.⏩
This is #113This is the clinical trial
https://clinicaltrials.gov/study/NCT04102189
A paper from that trial:
https://www.nejm.org/doi/full/10.1056/NEJMoa2208601
The FDA approval:
https://www.accessdata.fda.gov/drugs...ig1s005ltr.pdf
"REQUIRED PEDIATRIC ASSESSMENTS
Under the Pediatric Research Equity Act (PREA) (21 U.S.C. 355c), all applications for new active ingredients (which includes new salts and new fixed combinations), new indications, new dosage forms, new dosing regimens, or new routes of administration are required to contain an assessment of the safety and effectiveness of the product for the claimed indication in pediatric patients unless this requirement is waived, deferred,or inapplicable.
We note that you have fulfilled the pediatric study requirement for ages 12 to less than 18 years for this application. We remind you that there is a PREA postmarketing requirement listed in the June 4, 2021, approval letter that is still open. "
"FULFILLMENT OF POSTMARKETING REQUIREMENT
This sNDA contained the final report for the following postmarketing requirement listed in the June 4, 2021, approval letter:
4081-1 Complete the ongoing 68-week randomized, double-blind, placebocontrolled study to evaluate the safety and efficacy of semaglutide for the treatment of obesity in pediatric patients ages 12 to less than 18.
We have reviewed your submission and conclude that the above requirement was fulfilled.
We remind you that there are postmarketing requirements listed in the June 4, 2021, approval letter that are still open. "
It doesn't look like anyone is suggesting to "give kids ozempic".
https://clinicaltrials.gov/study/NCT04102189
A paper from that trial:
https://www.nejm.org/doi/full/10.1056/NEJMoa2208601
The FDA approval:
https://www.accessdata.fda.gov/drugs...ig1s005ltr.pdf
"REQUIRED PEDIATRIC ASSESSMENTS
Under the Pediatric Research Equity Act (PREA) (21 U.S.C. 355c), all applications for new active ingredients (which includes new salts and new fixed combinations), new indications, new dosage forms, new dosing regimens, or new routes of administration are required to contain an assessment of the safety and effectiveness of the product for the claimed indication in pediatric patients unless this requirement is waived, deferred,or inapplicable.
We note that you have fulfilled the pediatric study requirement for ages 12 to less than 18 years for this application. We remind you that there is a PREA postmarketing requirement listed in the June 4, 2021, approval letter that is still open. "
"FULFILLMENT OF POSTMARKETING REQUIREMENT
This sNDA contained the final report for the following postmarketing requirement listed in the June 4, 2021, approval letter:
4081-1 Complete the ongoing 68-week randomized, double-blind, placebocontrolled study to evaluate the safety and efficacy of semaglutide for the treatment of obesity in pediatric patients ages 12 to less than 18.
We have reviewed your submission and conclude that the above requirement was fulfilled.
We remind you that there are postmarketing requirements listed in the June 4, 2021, approval letter that are still open. "
It doesn't look like anyone is suggesting to "give kids ozempic".
Originally Posted By J.L.C.⏩
You haven't yet shared why you think 30% of weight lost is bone and muscle -for everyone
Of course losing muscle mass and bone density are not good.
However, suggesting these effects are universal and without any possible mitigation strategies seems disingenuous.
Of course negative side effects are not good.
I would say that's why these decisions should be made with critical evaluation of the case, and the assistance of a professional, to weigh the risks against the benefits.
Of course losing muscle mass and bone density are not good.
However, suggesting these effects are universal and without any possible mitigation strategies seems disingenuous.
Of course negative side effects are not good.
I would say that's why these decisions should be made with critical evaluation of the case, and the assistance of a professional, to weigh the risks against the benefits.
02-04-2024, 08:26 PM
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#138
- LargePeter
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Originally Posted By z4v4⏩
Yeah, c0ckLol. I always get a kick out of you dumb phaqgots. Remember what I eat, phaqgot?
RAW DOG CREW LIEUTENANT
ALL ROADS LEAD TO MENTZER
President Donald J Trump Crew
Steroids Crew
Growth Hormone Crew
Miscers Who Lift Crew
Robert Pickton Hooker Disposal Crew
Mustang Crew
No Alcohol Crew
Gay Phaggot Crew:
Papi Cholo
02-04-2024, 09:34 PM
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#139
- Paul Kreul
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Originally Posted By J.L.C.⏩
the side effects were severe enough for the FDA to release a warning for the drug..but you decided not to post that..any reason why?This is #16
This is #113
This is #113
02-05-2024, 05:27 AM
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#140
- Dave22reborn
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Originally Posted By d3th2trump⏩
Coming from the incel that wants to kill drug dealers?so every new drug from now on is going to have screeching now?
02-05-2024, 06:21 AM
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#141
02-05-2024, 06:49 AM
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#142
- Dave22reborn
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- Dave22reborn
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Originally Posted By ezmac31⏩
Seriously, what's with leftists and their love of Big Pharma??? Do they have stock in it???Good. These people deserve this scrutiny, they’ve earned it
02-05-2024, 06:52 AM
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#143
02-05-2024, 07:33 AM
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#144
02-05-2024, 09:09 AM
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#145
- JUSA
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Originally Posted By ezmac31⏩
Fascism is now questioning massive corporations or collusion between Government and Corporations. Let that sink in for a minute.Government and corporations are their religion now
The old adage was always that as you got older, you became more conservative.
I don't think that's the case with me at all. I've opened myself up to a lot of ideas that were, back in the day, firmly leftist. I don't wildly support capitalism, I am anti-war, I staunchly support free speech, I am a skeptic of the Government and massive corporations... and all those beliefs are suddenly 'far right', thanks to insane branding by the (corporate owned) media and the sad society that has sat back and not just let this happen, but lined up like lemmings to screech and support that narrative.
Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.
Why did you lie about my position? Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous? Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?
Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.
- Arthur Schopenhauer
02-05-2024, 09:24 AM
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#146
Originally Posted By JUSA⏩
Of course.Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.
Why did you lie about my position?Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous?Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?
Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
Why did you lie about my position?Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous?Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?
Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
02-05-2024, 09:29 AM
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#147
Originally Posted By JUSA⏩
I don't see why folks get upset about an approval without reviewing any of the information related to said approval.Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.
Why did you lie about my position? Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous? Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?
Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
Why did you lie about my position? Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous? Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?
Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
"In this double-blind, parallel-group, randomized, placebo-controlled trial, we enrolled adolescents (12 to <18 years of age) with obesity (a body-mass index [BMI] in the 95th percentile or higher) or with overweight (a BMI in the 85th percentile or higher) and at least one weight-related coexisting condition."
95th percentile.
https://www.cdc.gov/obesity/basics/c...-defining.html
Seems like an odd knee-jerk reaction

02-05-2024, 10:29 AM
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#148
- JUSA
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Originally Posted By J.L.C.⏩
Snipped and did not bother to read anything else.I don't see why folks get upset about an approval without reviewing any of the information related to said approval.
1) I wasn't particularly upset
2) It was about you making up lies and attributing them to me, not that
I hypothesized it was because your recognize your own shilling position is weak and you lack the integrity to be honest. Did anything I snipped address that or were you just dancing down your strawman and ignoring it, like you ignore anything that isn't pro-Big Pharm?
All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.
- Arthur Schopenhauer
02-05-2024, 10:41 AM
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#149
- CrimsonSteel
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https://www.federalregister.gov/docu...-risk-clinical
The Food and Drug Administration (FDA, the Agency, or we) is issuing a final rule to amend its regulations to implement a provision of the 21st Century Cures Act (Cures Act). This final rule allows an exception from the requirement to obtain informed consent when a clinical investigation poses no more than minimal risk to the human subject and includes appropriate safeguards to protect the rights, safety, and welfare of human subjects. The final rule permits an institutional review board (IRB) to waive or alter certain informed consent elements or to waive the requirement to obtain informed consent, under limited conditions, for certain FDA-regulated minimal risk clinical investigations.
This doesn't sound absolutely psychotic at all, no sir! Er...I mean, no ma'am.
The Food and Drug Administration (FDA, the Agency, or we) is issuing a final rule to amend its regulations to implement a provision of the 21st Century Cures Act (Cures Act). This final rule allows an exception from the requirement to obtain informed consent when a clinical investigation poses no more than minimal risk to the human subject and includes appropriate safeguards to protect the rights, safety, and welfare of human subjects. The final rule permits an institutional review board (IRB) to waive or alter certain informed consent elements or to waive the requirement to obtain informed consent, under limited conditions, for certain FDA-regulated minimal risk clinical investigations.
This doesn't sound absolutely psychotic at all, no sir! Er...I mean, no ma'am.
02-05-2024, 10:57 AM
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#150
- Dave22reborn
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Originally Posted By J.L.C.⏩
So your solution to everything is a pill or an injection.....I don't see why folks get upset about an approval without reviewing any of the information related to said approval.
"In this double-blind, parallel-group, randomized, placebo-controlled trial, we enrolled adolescents (12 to <18 years of age) with obesity (a body-mass index [BMI] in the 95th percentile or higher) or with overweight (a BMI in the 85th percentile or higher) and at least one weight-related coexisting condition."
95th percentile.
https://www.cdc.gov/obesity/basics/c...-defining.html
Seems like an odd knee-jerk reaction
"In this double-blind, parallel-group, randomized, placebo-controlled trial, we enrolled adolescents (12 to <18 years of age) with obesity (a body-mass index [BMI] in the 95th percentile or higher) or with overweight (a BMI in the 85th percentile or higher) and at least one weight-related coexisting condition."
95th percentile.
https://www.cdc.gov/obesity/basics/c...-defining.html
Seems like an odd knee-jerk reaction

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