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» Trust the Science: EXPERTS in the AAP, "Give kids Ozempic!"
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post 1697422133 02-04-2024, 05:25 PM
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#121
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Originally Posted By J.L.C.
You have options if you don't like what I post

This thread is about OP being upset that Ozempic has been approved as an option for morbidly obese teens.

I shared the source material on the trials and FDA decision
Right, just like it was an option flr morbidly obese adults..... How'd that turn out?

What is with you and this mindset of medication or an injection being the solution to a problem???
post 1697422183 02-04-2024, 05:25 PM
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#122
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Originally Posted By JUSA
Why do you keep saying I am upset?
Dunno. Maybe you're just "shilling"
Originally Posted By JUSA
https://www.theatlantic.com/health/a...-risks/674204/



Semaglutide is the active ingredient in Wegovy, Ozempic, and Rybelsus. AAP = American Academy of Pediatrics i.e. Experts and infallible, can not be wrong and you can not question them.

DO NOT BE ALARMED

The FDA has *Approved* Ozempic for both Adults and Teens!!! IT'S SAFE!

FDA approves high-dose semaglutide for adolescents with obesity
https://diabetes.medicinematters.com...esity/23902216

Please, give your developing children Ozempic. Take it yourself. Everyone must take Ozempic. Consume. It's FDA approved, that means: We know it is safe! Just cherish we live in the United States of America, one of the few countries that allow it.

Ignore anti-science CTards who talk about it fuking up people's guts or doing permanent damage and that people regain weight when they're off. The FDA has spoken: It's safe and CTards should be in prison for spreading misinformation. It should not be legal to question the FDA, AAP or The Science.
post 1697422623 02-04-2024, 05:40 PM
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#123
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Originally Posted By J.L.C.
Dunno. Maybe you're just "shilling"
You didnt even know about any of the negative side effects of Ozempic, but here you are, praising it like your precious Covid jab.....
post 1697423493 02-04-2024, 06:02 PM
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#124
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Originally Posted By Dave22reborn
You didnt even know about any of the negative side effects of Ozempic, but here you are, praising it like your precious Covid jab.....
What makes you think I wasn't aware of some effects?

What makes you think I'm "praising" anything?

OP got mad.

I shared source material.


post 1697424933 02-04-2024, 06:36 PM
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#125
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Originally Posted By J.L.C.
What makes you think I wasn't aware of some effects?

What makes you think I'm "praising" anything?

OP got mad.

I shared source material.


Why didn't you post any negative effects then?
post 1697426283 02-04-2024, 07:10 PM
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#126
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Originally Posted By J.L.C.
What makes you think I wasn't aware of some effects?

What makes you think I'm "praising" anything?

OP got mad.

I shared source material.


Probably because you didn't even know about the loss of bone density or muscle mass, or numerous other side effects, even though this has been known for years.....
post 1697426493 02-04-2024, 07:17 PM
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#127
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Originally Posted By JUSA
Who? I mean, type 2 is directly a result of diet/lifestyle. Someone may have a genetic disposition to be more inclined to get it, but bad diets will always be at the root of it.
These people:
Originally Posted By JUSA
The problem, greedy executives saw that a side-effect was massive weight loss - and here we are.
Deepfat: "I guarantee I beat you by at least 6 strokes. Afterwards, I'll slide my thick conservative cawk in your old lady just to finish the job."

z4: "So when are you available in September to play?"

Deep: "On second thought, I don't play golf with broads. You're such a scumbag that I'd be much more inclined to just slap the chit out of you."

z4: "MMA match works, too. So when are you available this month?

Deep: "I won't subject myself to being in the presence of a scumbag."
post 1697426513 02-04-2024, 07:17 PM
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#128
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Originally Posted By Paul
Why didn't you post any negative effects then?
Wat?

I posted the registered trial, the protocol, and the pub.
post 1697427823 02-04-2024, 07:52 PM
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#129
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Originally Posted By J.L.C.
Wat?

I posted the registered trial, the protocol, and the pub.
But you chose to disregard the negative facts, why?
post 1697428003 02-04-2024, 07:54 PM
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#130
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Originally Posted By Paul
But you chose to disregard the negative facts, why?
I don't think that happened.

You in on the misc analysis jam?
post 1697428013 02-04-2024, 07:55 PM
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#131
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Post deleted by user
post 1697428163 02-04-2024, 07:57 PM
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#132
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Originally Posted By J.L.C.
I don't think that happened.

You in on the misc analysis jam?
post number you reference negative sides?
post 1697428323 02-04-2024, 08:00 PM
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#133
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Originally Posted By Paul
post number you reference negative sides?
Part of the trial results
post 1697428393 02-04-2024, 08:02 PM
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#134
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Originally Posted By J.L.C.
Part of the trial results
oh okay..you just chose not to discuss that part of the trial results?
post 1697428513 02-04-2024, 08:04 PM
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#135
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Originally Posted By Paul
oh okay..you just chose not to discuss that part of the trial results?
Which part did I discuss?
post 1697428943 02-04-2024, 08:13 PM
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#136
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Originally Posted By J.L.C.
Which part did I discuss?
post number you reference negative sides?
post 1697429143 02-04-2024, 08:18 PM
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#137
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Originally Posted By Paul
post number you reference negative sides?
This is #16
Originally Posted By J.L.C.
This is the clinical trial
https://clinicaltrials.gov/study/NCT04102189


A paper from that trial:
https://www.nejm.org/doi/full/10.1056/NEJMoa2208601


The FDA approval:

https://www.accessdata.fda.gov/drugs...ig1s005ltr.pdf

"REQUIRED PEDIATRIC ASSESSMENTS

Under the Pediatric Research Equity Act (PREA) (21 U.S.C. 355c), all applications for new active ingredients (which includes new salts and new fixed combinations), new indications, new dosage forms, new dosing regimens, or new routes of administration are required to contain an assessment of the safety and effectiveness of the product for the claimed indication in pediatric patients unless this requirement is waived, deferred,or inapplicable.

We note that you have fulfilled the pediatric study requirement for ages 12 to less than 18 years for this application. We remind you that there is a PREA postmarketing requirement listed in the June 4, 2021, approval letter that is still open. "


"FULFILLMENT OF POSTMARKETING REQUIREMENT

This sNDA contained the final report for the following postmarketing requirement listed in the June 4, 2021, approval letter:

4081-1 Complete the ongoing 68-week randomized, double-blind, placebocontrolled study to evaluate the safety and efficacy of semaglutide for the treatment of obesity in pediatric patients ages 12 to less than 18.

We have reviewed your submission and conclude that the above requirement was fulfilled.

We remind you that there are postmarketing requirements listed in the June 4, 2021, approval letter that are still open. "

It doesn't look like anyone is suggesting to "give kids ozempic".
This is #113
Originally Posted By J.L.C.
You haven't yet shared why you think 30% of weight lost is bone and muscle -for everyone

Of course losing muscle mass and bone density are not good.

However, suggesting these effects are universal and without any possible mitigation strategies seems disingenuous.

Of course negative side effects are not good.

I would say that's why these decisions should be made with critical evaluation of the case, and the assistance of a professional, to weigh the risks against the benefits.
post 1697429483 02-04-2024, 08:26 PM
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#138
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Originally Posted By z4v4
Lol. I always get a kick out of you dumb phaqgots. Remember what I eat, phaqgot?
Yeah, c0ck
RAW DOG CREW LIEUTENANT

ALL ROADS LEAD TO MENTZER

President Donald J Trump Crew
Steroids Crew
Growth Hormone Crew
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Robert Pickton Hooker Disposal Crew
Mustang Crew
No Alcohol Crew

Gay Phaggot Crew:
Papi Cholo
post 1697431523 02-04-2024, 09:34 PM
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#139
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Originally Posted By J.L.C.
This is #16






This is #113
the side effects were severe enough for the FDA to release a warning for the drug..but you decided not to post that..any reason why?
post 1697438493 02-05-2024, 05:27 AM
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#140
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Originally Posted By d3th2trump
so every new drug from now on is going to have screeching now?
Coming from the incel that wants to kill drug dealers?
post 1697439523 02-05-2024, 06:21 AM
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#141
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Originally Posted By d3th2trump
so every new drug from now on is going to have screeching now?
Good. These people deserve this scrutiny, they’ve earned it
post 1697440193 02-05-2024, 06:49 AM
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#142
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Originally Posted By ezmac31
Good. These people deserve this scrutiny, they’ve earned it
Seriously, what's with leftists and their love of Big Pharma??? Do they have stock in it???
post 1697440223 02-05-2024, 06:52 AM
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#143
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Originally Posted By Dave22reborn
Seriously, what's with leftists and their love of Big Pharma??? Do they have stock in it???
From "Occupy Wallstreet" to this...
post 1697441553 02-05-2024, 07:33 AM
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#144
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Originally Posted By Dave22reborn
Seriously, what's with leftists and their love of Big Pharma??? Do they have stock in it???
Government and corporations are their religion now
post 1697444643 02-05-2024, 09:09 AM
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#145
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Originally Posted By ezmac31
Government and corporations are their religion now
Fascism is now questioning massive corporations or collusion between Government and Corporations. Let that sink in for a minute.

The old adage was always that as you got older, you became more conservative.

I don't think that's the case with me at all. I've opened myself up to a lot of ideas that were, back in the day, firmly leftist. I don't wildly support capitalism, I am anti-war, I staunchly support free speech, I am a skeptic of the Government and massive corporations... and all those beliefs are suddenly 'far right', thanks to insane branding by the (corporate owned) media and the sad society that has sat back and not just let this happen, but lined up like lemmings to screech and support that narrative.

Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.

Why did you lie about my position? Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous? Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?

Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.

- Arthur Schopenhauer
post 1697444983 02-05-2024, 09:24 AM
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#146
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Originally Posted By JUSA
Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.

Why did you lie about my position?Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous?Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?

Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
Of course.
post 1697445133 02-05-2024, 09:29 AM
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#147
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Originally Posted By JUSA
Btw, JLC, you lied and said I was upset about doctors prescribing this medicine to "morbidlyobese" children. Cite where I said that. There is a pretty big difference between an obese individual and a morbidly obese one, something like 10 whopping BMI points.

Why did you lie about my position? Is yours honestly so weak and obviously shilling that you could not simply take my actual position and critique it? Did you feel you had to openly and blatantly lie about me in order to try and make my position seem more wild and outrageous? Can you explain why you lied about me during this exchange? Like when you repeatedly misstated my comment about the trials being done in Europe?

Why is it you must lie about others? You say you're not invested in this and just some neutral bystander, but then you sit around and lie and twist things - so it's clear you are lying once again about your neutrality.
I don't see why folks get upset about an approval without reviewing any of the information related to said approval.

"In this double-blind, parallel-group, randomized, placebo-controlled trial, we enrolled adolescents (12 to <18 years of age) with obesity (a body-mass index [BMI] in the 95th percentile or higher) or with overweight (a BMI in the 85th percentile or higher) and at least one weight-related coexisting condition."

95th percentile.

https://www.cdc.gov/obesity/basics/c...-defining.html

Seems like an odd knee-jerk reaction
post 1697447633 02-05-2024, 10:29 AM
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#148
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Originally Posted By J.L.C.
I don't see why folks get upset about an approval without reviewing any of the information related to said approval.
Snipped and did not bother to read anything else.

1) I wasn't particularly upset
2) It was about you making up lies and attributing them to me, not that

I hypothesized it was because your recognize your own shilling position is weak and you lack the integrity to be honest. Did anything I snipped address that or were you just dancing down your strawman and ignoring it, like you ignore anything that isn't pro-Big Pharm?
All truth passes through three stages. First, it is ridiculed. Second, it is violently opposed. Third, it is accepted as being self-evident.

- Arthur Schopenhauer
post 1697448003 02-05-2024, 10:41 AM
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#149
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https://www.federalregister.gov/docu...-risk-clinical

The Food and Drug Administration (FDA, the Agency, or we) is issuing a final rule to amend its regulations to implement a provision of the 21st Century Cures Act (Cures Act). This final rule allows an exception from the requirement to obtain informed consent when a clinical investigation poses no more than minimal risk to the human subject and includes appropriate safeguards to protect the rights, safety, and welfare of human subjects. The final rule permits an institutional review board (IRB) to waive or alter certain informed consent elements or to waive the requirement to obtain informed consent, under limited conditions, for certain FDA-regulated minimal risk clinical investigations.


This doesn't sound absolutely psychotic at all, no sir! Er...I mean, no ma'am.
post 1697448653 02-05-2024, 10:57 AM
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#150
  1. Dave22reborn
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Originally Posted By J.L.C.
I don't see why folks get upset about an approval without reviewing any of the information related to said approval.

"In this double-blind, parallel-group, randomized, placebo-controlled trial, we enrolled adolescents (12 to <18 years of age) with obesity (a body-mass index [BMI] in the 95th percentile or higher) or with overweight (a BMI in the 85th percentile or higher) and at least one weight-related coexisting condition."

95th percentile.

https://www.cdc.gov/obesity/basics/c...-defining.html

Seems like an odd knee-jerk reaction
So your solution to everything is a pill or an injection.....
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